Recruiting

Lacrifill

Sponsor:

Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists

Code:

NCT07510620

Conditions

Dry Eye

Eligibility Criteria

Sex: All

Age: 22+

Healthy Volunteers: Not accepted

Interventions

Lacrifill

Study Details

Brief summary:

This research study is to see if using Lacrifill is safe, easy to use, and helpful for people who wear contact lenses but can't wear them comfortably for long. Specifically, the study aims to determine whether regular use of Lacrifill over a 2-3 month period can help people wear their contacts longer without discomfort and reduce signs and symptoms of dry eye.

Conditions

Dry Eye

Study ID

NCT07510620

Start date

Dec 12, 2025

Status verified date

Apr, 2026

Completion date

Aug, 2026

Anticipated

Primary completion date

Jul, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 22+

Healthy Volunteers: Not accepted

Inclusion Criteria

  • >21 years of age
  • Contact lens wearer
  • Previous Dry Eye Treatment
  • Be on a stable dose of antihistamines/Birth Control Medication and Lifitegrast and cyclosporine.
  • Schrimers Anesthetized less than or equal to 10
  • CLDEQ-8 greater than or equal to 12
  • Corneal Staining NEI grading scale greater than or equal to 1

Exclusion Criteria:

  • Known allergy to Hyaluronic Acid
  • Current topical ophthalmic drops other than dry eye treatment
  • Uncontrolled Diabetes
  • Diabetic Retinopathy
  • Pregnancy or Lactating
  • Corneal Surgery (except Refractive)
  • Corneal Scars
  • Keratoconus
  • Ocular Herpetic Keratitis

Study Design

Enrollment

30 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Lacrifill

Interventions

Lacrifill

Lacrifill is a cross-linked hyaluronic acid derivative that temporarily blocks tear drainage, allowing patients eyed to be bathed in their own natural tears.

Primary outcome measure

  • Dry eye signs [ Time Frame: 2-3 months ]
  • Dry Eye Symptoms [ Time Frame: 2-3 Months ]
  • Contact Lens Tolerability [ Time Frame: 2-3 Months ]

Central Contacts and Locations

Central contacts

Patti Myers, COT

5707145910patti.myers@vipeyes.com

Cheryl Bayley

5707145915

Locations

Eye Care Specialists

Recruiting

Kingston, Pennsylvania, United States, 18704

Contacts

Patti Myers

877-489-7405patti.myers@vipeyes.com

More Information

Sponsor

Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists

Last update posted

Apr 3, 2026

Last verified

Apr, 2026

Keywords

  • Dry Eye
  • Lacrifill
  • contact lenses

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists on 2026-04-03.