Recruiting

FANS vs. CVAC

Sponsor:

Ohio State University

Code:

NCT07514351

Conditions

Kidney Stones

Nephrolithiasis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

ureteroscopy

CVAC

Study Details

Brief summary:

Improvements in ureteroscopes have led to improved stone free rates. Two new devices (FANS - Flexible and Navigable Suction) and the CVAC ureteroscope have never been compared head to head. This trial will compare these two new suction ureteroscope technologies against each other

Conditions

Kidney Stones

Nephrolithiasis

Study ID

NCT07514351

Start date

Jul 1, 2026

Status verified date

Mar, 2026

Completion date

Dec, 2028

Anticipated

Primary completion date

Jun, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Clinical diagnosis of Nephrolithiasis
  • Total linear stone diameter 8-20 mm in size

Exclusion Criteria:

  • Severe medical comorbidities causing inability to undergo general anesthesia

Study Design

Enrollment

159 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: FANS

Flexible and Navigable Suction Ureteroscopy

active comparator: CVAC

CVAC suction ureteroscopy arm

Interventions

ureteroscopy

ureteroscopy will be performed with flexible and navigable suction sheaths

CVAC

CVAC suction ureteroscopy will be used

Primary outcome measure

  • stone free rate [ Time Frame: up to six weeks ]

Central Contacts and Locations

Central contacts

Matthew Lee, MD

614-685-9181matthew.lee@osumc.edu

Locations

Ohio State University

Recruiting

Columbus, Ohio, United States, 43212

Contacts

Matthew Lee

614-293-8155matthew.lee@osumc.edu

More Information

Sponsor

Ohio State University

Last update posted

Oct 16, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-18. This information was provided to ClinicalTrials.gov by Ohio State University on 2026-10-16. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.