Recruiting

Observational Study

Sponsor:

Jaeb Center for Health Research

Code:

NCT07518134

Conditions

Uveitis

Eligibility Criteria

Sex: All

Age: 0 - 17

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The goal of this observational study is to collect data regarding clinical features and current/past treatments in children under 18 with uveitis. The main questions it aims to answer are:

  • What are the frequency of uveitis subtypes in children?
  • What are clinical and demographic characteristics overall and within each type of uveitis?

Participants will complete one enrollment visit with their doctor. Participants with uveitis onset <6 months from enrollment date will also partake in a 12 month chart review.

Conditions

Uveitis

Study ID

NCT07518134

Start date

Apr 14, 2026

Status verified date

May, 2026

Completion date

Apr, 2028

Anticipated

Primary completion date

Apr, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 17

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age:

  • Incident cases (onset ≤ 6 months) <17 years
  • Established cases (onset > 6 months) <18 years
  • Diagnosis of any type of uveitis (infectious or noninfectious) in any location except traumatic and post-operative uveitis.
  • Active or inactive uveitis with any treatment status (current / prior / none \[but under surveillance\]).

Exclusion Criteria:

  • Bilateral uveitis with differing etiologies
  • Traumatic uveitis
  • Post-operative uveitis
  • Immediate family member (spouse, biological or legal guardian, child, sibling, parent) who is an investigative site personnel directly affiliated with this study or who is an employee of JAEB Center for Health Research.
  • Ocular disease related to Retinoblastoma, Coat's disease, retinitis pigmentosa, inherited retinal degeneration, Juvenile xanthogranuloma (JXG), or leukemia/malignancy within the eye.

Study Design

Enrollment

300 participants

Anticipated

Interventions and Outcome Measures

Arms

Children diagnosed with uveitis - established cases

Children diagnosed with uveitis (onset > 6 months), either active or inactive with or without current treatment at time of enrollment.

Children diagnosed with uveitis - incident cases

Children diagnosed with uveitis (onset ≤ 6 months), either active or inactive with or without current treatment at time of enrollment.

Primary outcome measure

  • Frequency of uveitis subtypes in children <18 years of age [ Time Frame: Enrollment ]

Central Contacts and Locations

Central contacts

Julianne Zawadzki, MSPH

813-975-8690jrobinson@jaeb.org

Raymond Kraker, MSPH

8139758690rkraker@jaeb.org

Locations

Department of Ophthalmology, Boston University School of Medicine

Recruiting

Boston, Massachusetts, United States, 02118

Contacts

Kara C LaMattina, MD

617-414-4020Kara.LaMattina@bmc.org

Akron Children's Hospital

Recruiting

Akron, Ohio, United States, 44308

Contacts

Cassandra S Solis, O.D

330-543-5150csolis@akronchildrens.org

Cincinnati Children's Hospital Medical Center

Recruiting

Cincinnati, Ohio, United States, 45229

Contacts

Virginia Miraldi Utz, MD

513-636-4751virginia.utz@cchmc.org

Pediatric Ophthalmology Associates, Inc.

Recruiting

Columbus, Ohio, United States, 43205

Contacts

Catherine O Jordan, MD

(614) 224-6222cateolsonjordan@gmail.com

More Information

Sponsor

Jaeb Center for Health Research

Last update posted

May 8, 2026

Last verified

May, 2026

Keywords

  • pediatric
  • uveitis

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Jaeb Center for Health Research on 2026-05-08.