Recruiting

HIIT

Sponsor:

University of Miami

Code:

NCT07518888

Conditions

Prostate Cancer

Eligibility Criteria

Sex: Male

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

High-Intensity Interval Training (HIIT) Exercise

Study Details

Brief summary:

The purpose of this research study is to understand how a short session of a home-based bodyweight high-intensity interval training (HIIT) affects steroid hormone levels in men on active surveillance for low-grade prostate cancer.

Conditions

Prostate Cancer

Study ID

NCT07518888

Start date

Nov 30, 2026

Status verified date

Oct, 2026

Completion date

Feb, 2029

Anticipated

Primary completion date

Feb, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Male

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Males 18 to 80 years old
  • Diagnosis of localized prostate cancer
  • Currently under active surveillance
  • Ability to perform moderate-to-high intensity physical activity as demonstrated by self-assessment using the Physical Activity Readiness Questionnaire (PAR-Q+)
  • Able to independently perform activities of daily living, without limitations in mobility
  • Ability to read, write, speak, and understand English
  • Able and willing to sign consent and comply with study requirements

Exclusion Criteria:

  • Males currently receiving treatment for prostate cancer
  • Diagnosis of metastatic prostate cancer
  • Individuals with medical conditions contraindicating exercise
  • Uncontrolled cardiovascular or circulatory diseases, hypertension, and diabetes, as determined by the study doctor or treating physician
  • Ongoing use of medications affecting steroid metabolism
  • Unable to sign consent and/or comply with study requirements

Study Design

Enrollment

50 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Home-Based High Intensity Interval Training (HIIT) Exercise Session + Saliva Collection

Participants will complete a single supervised, online high intensity interval training (HIIT) exercise session performed at a moderate-to-high intensity lasting approximately 20 minutes. Saliva samples will be collected immediately prior to exercise, immediately following exercise (0-5 minutes), and 15-20 minutes post-exercise.

Interventions

High-Intensity Interval Training (HIIT) Exercise

Participants will complete a single supervised, online high intensity interval training (HIIT) exercise session lasting approximately 20 minutes. The exercise protocol consists of 3 rounds of moderate to high intensity bodyweight exercises, including movements such as hip thrusts, lateral squats, wall pushups, lat pull downs, lunges, and jumping jacks.

Primary outcome measure

  • Protocol Completion Rate [ Time Frame: From enrollment through completion of all study procedures (up to Day 1) ]

Central Contacts and Locations

Central contacts

Nima Sharifi, MD

305-243-1350nimasharifi@miami.edu

Elena Cortizas, MS

(305) 243-3593ecortizas@med.miami.edu

Locations

University of Miami Hospitals and Clinics

Recruiting

Miami, Florida, United States, 33141

Contacts

Elena Cortizas, MS

(305) 243-3593ecortizas@med.miami.edu

More Information

Sponsor

University of Miami

Last update posted

Oct 23, 2026

Last verified

Oct, 2026

Keywords

  • Prostate Cancer
  • Exercise
  • Steroids
  • Active Surveillance

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-24. This information was provided to ClinicalTrials.gov by University of Miami on 2026-10-23. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.