Recruiting

Vagus Nerve Stimulation

Sponsor:

Youngstown State University

Code:

NCT07528742

Conditions

Healthy Subjects (HS)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

vagus nerve stimulation

Study Details

Brief summary:

Non-Invasive Vagus Nerve Stimulation will be provided to the participants using a transcutaneous electrical nerve stimulation (TENS) unit, a routine physical therapy intervention by the faculty researcher who is a licensed physical therapist. The electrodes will be clipped to ear over the vagus nerve distribution area. The parameters will be 30 Hz, 250 us, 5 minutes, at tolerance (no pain). Reaction time will test collected pre and post the stimulation using online reaction time testing platform.

Conditions

Healthy Subjects (HS)

Study ID

NCT07528742

Start date

Apr 6, 2026

Status verified date

Apr, 2026

Completion date

Apr 5, 2027

Anticipated

Primary completion date

Apr 5, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Healthy participants over the age of 18
  • did not receive vagus nerve stimulation previously

Exclusion Criteria:

  • alcohol or drug abuse
  • metal in the skull
  • implanted cardiac or cranial devices
  • Women during 3 trimester of pregnancy

Study Design

Enrollment

30 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: vagus nerve stimulation

Non-Invasive Vagus Nerve Stimulation will be provided to the participants using a transcutaneous electrical nerve stimulation (TENS) unit, a routine physical therapy intervention by the faculty researcher who is a licensed physical therapist. The electrodes will be clipped to ear over the vagus nerve distribution area. The parameters will be 30 Hz, 250 us, 5 minutes, at tolerance (no pain).

Interventions

vagus nerve stimulation

Non-Invasive Vagus Nerve Stimulation will be provided to the participants using a transcutaneous electrical nerve stimulation (TENS) unit, a routine physical therapy intervention by the faculty researcher who is a licensed physical therapist. The electrodes will be clipped to ear over the vagus nerve distribution area. The parameters will be 30 Hz, 250 us, 5 minutes, at tolerance (no pain)

Primary outcome measure

  • Reaction time [ Time Frame: Baseline and immediately after the intervention. ]

Central Contacts and Locations

Central contacts

Weiqing Ge Ge, DPT, PhD

330-941-2702wge@ysu.edu

Locations

Youngstown State University

Recruiting

Youngstown, Ohio, United States, 44555

Contacts

Weiqing Ge, DPT, PhD

330-941-2702wge@ysu.edu

Cathy Parrott, PhD

330 941-2559cbieberparrott@ysu.edu

Principal Investigator:

Weiqing Ge, DPT, PhD

More Information

Sponsor

Youngstown State University

Last update posted

Apr 14, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Youngstown State University on 2026-04-14.