Recruiting

Peer Support Specialist

Sponsor:

Prisma Health-Upstate

Code:

NCT07541417

Conditions

Opioid Use Disorder

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Certified Peer Support Specialist Intervention

Study Details

Brief summary:

This study will provide longitudinal data for 6-months on a target sample of patients with Opioid Use Disorder (OUD) recruited from Prisma Health Mobile Health Clinics in South Carolina. The goal of our study is to increase OUD treatment initiation and retention and maximize prevention of overdose deaths in underserved communities through development, testing, and delivery of a novel intervention targeting areas of optimal allocation of MHC with a Peer Support Specialist (PSS) intervention.

Conditions

Opioid Use Disorder

Study ID

NCT07541417

Start date

Apr 8, 2026

Status verified date

Apr, 2026

Completion date

Aug 31, 2029

Anticipated

Primary completion date

Feb 28, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age 18+
  • Have diagnosis of OUD
  • New mobile health MOUD patient

Exclusion Criteria:

  • Unable to read and comprehend the consent materials and other study materials
  • Currently working with a Certified Peer Support Specialist
  • Having severe medical or psychiatric disability that would hinder participation in the study, as determined by the clinical provider

Study Design

Enrollment

750 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

no intervention: Standard of Care

The control condition involves the standard mobile recovery program (MRP) protocol. The MRP MOUD-specific capabilities are providing screening and assessments; induction monitoring; maintenance buprenorphine treatment; and follow-up care. The MRP is a facilitator of MOUD induction through partnerships with 340B pharmacies. Participants in both the standard of care condition and CPSS condition will receive MRP services for OUD screening, treatment, and overdose prevention, including enrollment in MOUD treatment and provision of take-home naloxone, fentanyl and/or xylazine test strips as needed.

experimental: Certified Peer Intervention Specialist

The intervention includes standard of care described above and also involves a participant meeting with a certified peer support specialist (CPSS) throughout MOUD initiation and early maintenance phases (up to 24 weeks post-initiation). CPSS encounters may be in-person or virtual. CPSS will track their services provided throughout the study period utilizing the newly developed checklist, incorporated into REDCap.

Interventions

Certified Peer Support Specialist Intervention

Participants are recruited from mobile health clinics (MHC) delivered to communities using a predictive modeling framework to target areas for optimal MHC allocation to maximize prevention of overdose deaths. Patients randomized to the intervention arm are linked to a peer support specialist. Peer support specialists are Certified Peer Support Specialists (CPSS) who have lived experience with Opioid Use Disorder (OUD) and OUD recovery. Peer support specialists offer consistent personalized recovery support and generalized social support based on a peer support checklist. Peer support specialists will maintain contact and provide support for the participant for 6 months post-baseline, following a peer support manual.

Primary outcome measure

  • Medications for Opioid Use Disorder (MOUD) Initiation [ Time Frame: 3 months ]
  • Medications for Opioid Use Disorder (MOUD) Retention [ Time Frame: 6 months ]

Central Contacts and Locations

Locations

Prisma Health Upstate

Recruiting

Greenville, South Carolina, United States, 29605

Contacts

More Information

Sponsor

Prisma Health-Upstate

Last update posted

Apr 28, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Prisma Health-Upstate on 2026-04-28.