Recruiting

rPMS

Sponsor:

University of Manitoba

Code:

NCT07544914

Conditions

Tennis Elbow Syndrome

Golfer's Elbow

Carpal Tunnel Syndrome (CTS)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Two days Active rPMS

Two days Sham rPMS

Study Details

Brief summary:

This pilot, randomized, sham-controlled, single-blind study will evaluate the effectiveness of repetitive peripheral magnetic stimulation (rPMS) in reducing pain in adults with tennis/golfer's elbow or carpal tunnel syndrome. Approximately 40 participants will be randomly assigned to active or sham stimulation delivered over two consecutive days. Outcomes, including pressure pain threshold, subjective pain ratings, and local tissue oxygenation (fNIRS), will be assessed at baseline, immediately post-intervention, and during follow-up up to 6 months to evaluate both clinical effects and underlying physiological mechanisms.

Conditions

Tennis Elbow Syndrome

Golfer's Elbow

Carpal Tunnel Syndrome (CTS)

Study ID

NCT07544914

Start date

Jul 1, 2026

Status verified date

Sep, 2026

Completion date

Dec 30, 2027

Anticipated

Primary completion date

Aug 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Clinical diagnosis or self-reported history consistent with either medial or lateral epicondylitis or carpal tunnel syndromes.
  • Presence of chronic pain in the target area (mentioned above) at the time of enrollment.
  • Ability to understand the study procedures and provide informed consent.

Exclusion Criteria:

  • Contraindications to peripheral magnetic stimulation, including implanted electronic medical devices or metallic implants in locations deemed unsafe for stimulation.
  • Open wounds, active skin conditions, or other local conditions at the stimulation site.
  • Current neurological, musculoskeletal, or systemic medical conditions that, in the opinion of the investigators, would interfere with safe participation or interpretation of study outcomes.
  • Current upper-limb injury or condition other than tennis/golfer elbow or carpal tunnel syndromes that could confound pain or perfusion measurements.
  • Pregnancy.
  • Inability to tolerate the stimulation or measurement procedures.
  • Inability to adequately understand study instructions or provide informed consent.

Study Design

Enrollment

40 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Two days active rPMS - Tennis/golfer syndrome

Participants of this arm, suffer from chronic pain at elbow either medial or lateral epicondylitis (tennis/golder syndromes) and receive real rPMS pulses as treatment for two days successively, each day 300 pulses at 10 Hz.

sham comparator: Two days sham rPM - Tennis/golfer syndrome

Participants of this arm, suffer from chronic pain at elbow either medial or lateral epicondylitis (tennis/golder syndromes) and receive SHAM rPMS pulses as treatment for two days successively, each day 300 pulses at 10 Hz.

experimental: Two days Active rPMS - Carpal Tunnel Syndrome

Participants of this arm, suffer from chronic pain at wrist (carpal tunnel syndrome) and receive REAL rPMS pulses as treatment for two days successively, each day 300 pulses at 10 Hz.

sham comparator: Two days Sham rPMS - Carpal Tunnel syndrome

Participants of this arm, suffer from chronic pain at wrist (carpal tunnel syndrome) and receive SHAM rPMS pulses as treatment for two days successively, each day 300 pulses at 10 Hz.

Interventions

Two days Active rPMS

It is a magnetic coil with a device that creates electromagnetic pulses. The Real one gives pulses with 100% intensity.

Two days Sham rPMS

Sham coil gives very weak pulses off target that does not penetrate to the skin.

Primary outcome measure

  • Change in pain pressure threshold (PPT) [ Time Frame: from baseline to post-treatment assessments on day 3 and week2 up to 6 months follow-up. ]

Central Contacts and Locations

Central contacts

Mari Garcia, M.Sc.

(204) 478-6352MARITERE.GARCIACAMPUZANO@umanitoba.ca

Zahra Moussavi, Ph.D.

204-474-7023Zahra.Moussavi@umanitoba.ca

Locations

Riverview Health Center

Recruiting

Winnipeg, Manitoba, Canada, R3L 2P4

Contacts

Cassandra Aldaba, M.Sc.

204-478-6163umaldabc@myumanitoba.ca

More Information

Sponsor

University of Manitoba

Last update posted

Sep 29, 2026

Last verified

Sep, 2026

Keywords

  • rPMS
  • elbow
  • wrist
  • chronic pain
  • NIRS

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-30. This information was provided to ClinicalTrials.gov by University of Manitoba on 2026-09-29. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.