Recruiting

Hypertension Management

Sponsor:

Rush University Medical Center

Code:

NCT07547345

Conditions

Hypertension

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Community-Based Multidisciplinary Hypertension Management Program

Study Details

Brief summary:

The Live Healthy Chicago (LHC) Community Pilot is a prospective, community-based study evaluating the feasibility, effectiveness, and economic impact of a pharmacist-led hypertension management program delivered in trusted community settings on the West and South Sides of Chicago. Adults with uncontrolled hypertension will be identified and enrolled through community-based organizations, where a mobile clinical team-including community health workers, a pharmacist, and a registered nurse-will provide blood pressure screening, medication management, health education, and care coordination over a 3-month period. The study will assess participant engagement and acceptability, changes in systolic blood pressure. This pilot aims to address disparities in hypertension control by improving access to care in underserved communities and informing scalable, community-based models of chronic disease management.

Conditions

Hypertension

Study ID

NCT07547345

Start date

Feb 20, 2026

Status verified date

Apr, 2026

Completion date

Mar, 2027

Anticipated

Primary completion date

Mar, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adults 18 years or older
  • Record of two blood pressure readings of SBP>130 on two separate occasions (days) within the past 3 months

Exclusion Criteria:

  • Person is receiving dialysis
  • Person has had a heart or kidney transplant
  • Person is pregnant

Study Design

Enrollment

200 participants

Anticipated

Intervention Model

Single group

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Live Healthy Chicago Intervention

Participants receive a 12-week community-based hypertension management intervention delivered by a mobile clinical team including community health workers, registered nurses, and pharmacists. The intervention includes blood pressure monitoring, medication management under a collaborative practice agreement with a physician, health education, social needs screening, and care coordination.

Interventions

Community-Based Multidisciplinary Hypertension Management Program

A 12-week community-based hypertension management intervention delivered in community settings. The program includes pharmacist-led medication management under collaborative practice agreement, RN-led clinical monitoring and follow-up, and CHW-led outreach, education, and care navigation. Participants receive blood pressure screening, medication titration when indicated, home blood pressure monitoring support, and linkage to primary care and social services.

Primary outcome measure

  • Change in Systolic Blood Pressure (SBP) [ Time Frame: Baseline to 3 months (12 weeks) ]

Central Contacts and Locations

Central contacts

Elizabeth Lynch, PhD

312-563-2254Elizabeth_Lynch@rush.edu

Rebecca Dawar, MPH

312-942-8571Rebecca_Dawar@rush.edu

Locations

Rush University Medical Center

Recruiting

Chicago, Illinois, United States, 60612

Contacts

Elizabeth Lynch, PhD

312-563-2254Elizabeth_Lynch@rush.edu

Rebecca Dawar, MPH

312-942-8571Rebecca_Dawar@rush.edu

Principal Investigator:

Elizabeth Lynch, PhD

More Information

Sponsor

Rush University Medical Center

Last update posted

Apr 23, 2026

Last verified

Apr, 2026

Keywords

  • Hypertension
  • Blood Pressure Control
  • Cardiovascular Disease Prevention
  • Pharmacist-Led Care
  • Community-Based Intervention
  • Community Health Workers
  • Mobile Health Services
  • Medication Management
  • Medication Adherence
  • Health Disparities
  • Underserved Populations
  • Social Determinants of Health
  • Care Coordination
  • Chronic Disease Management
  • Preventive Cardiology
  • Urban Health
  • Feasibility Study
  • Pilot Study
  • Cost-Effectiveness
  • Population Health

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Rush University Medical Center on 2026-04-23.