Recruiting

Ankle Arthroscopy

Sponsor:

University of Missouri-Columbia

Code:

NCT07553221

Conditions

Pilon Fractures

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Diagnostic Ankle Nano-Arthroscopy

Study Details

Brief summary:

Patients with pilon fractures have a high incidence of talar osteochondral lesions. In this study, patients will undergo ankle arthroscopy at the time of external fixation. The objective is to help determine the incidence of these lesions with pilon fractures and to see if these nano-arthroscopy results change the plan for definitive treatment.

Conditions

Pilon Fractures

Study ID

NCT07553221

Start date

Apr 15, 2026

Status verified date

Jun, 2026

Completion date

Apr, 2031

Anticipated

Primary completion date

Apr, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥ 18 years (skeletally mature) Tibial plafond fractures with impaction of the articular surface requiring external fixation for temporization AO/Orthopaedic Trauma Association (OTA) Fracture classification 43-C type fractures (excluding posterior pilon or supination-adduction type ankle fractures) Closed injury

Exclusion Criteria:

  • Prior ankle surgery

  • Pre-existing ankle arthritis
  • Unstable polytrauma patients precluding safe temporization
  • Concomitant talus or calcaneus fractures identifiable on plain radiographs
  • Pregnant
  • Prisoner
  • Unable to Consent

Study Design

Enrollment

25 participants

Anticipated

Intervention Model

Single group

Primary purpose

Screening

Interventions and Outcome Measures

Arms

experimental: Diagnostic Ankle Nano-Arthroscopy

Following placement of the external fixator, the Arthrex Nanoscope will be introduced into the tibiotalar joint to evaluate for osteochondral lesions.

Interventions

Diagnostic Ankle Nano-Arthroscopy

Following placement of the external fixator, the Arthrex Nanoscope will be introduced into the tibiotalar joint to evaluate for osteochondral lesions

Primary outcome measure

  • The total number of patients with talar osteochondral lesions in patients with tibial plafond fractures as determined by using images from the nano-arthroscopy at the time of external fixation [ Time Frame: Perioperative ]

Central Contacts and Locations

Central contacts

Vicki L Jones, MEd

573-882-7583jonesvicki@health.missouri.edu

Locations

University of Missouri - Columbia

Recruiting

Columbia, Missouri, United States, 65201

Contacts

Vicki L Jones, MEd

573-882-7583jonesvicki@health.missouri.edu

Principal Investigator:

Brett Crist, MD

More Information

Sponsor

University of Missouri-Columbia

Last update posted

Jul 30, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Missouri-Columbia on 2026-07-30.