Recruiting

ASSIST

Sponsor:

Patrick C. Johnson, MD

Code:

NCT07553572

Conditions

Breast Cancer (Locally Advanced or Metastatic)

Lymphoma

Colorectal Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

ASSIST phone application

Study Details

Brief summary:

The goal of this clinical trial is to learn if an artificial intelligence phone application called ASSIST can help patients receiving cancer treatment.

The main question\[s\] it aims to answer are:

Is ASSIST feasible for patients (meaning can it be used by patients)? Is ASSIST acceptable to patients (meaning do patients like it)?

Researchers will compare the ASSIST phone application to see how it compares to usual clinical care.

Participants on the ASSIST arm will use the ASSIST phone application for 12 weeks, and participants in both groups will complete surveys.

Conditions

Breast Cancer (Locally Advanced or Metastatic)

Lymphoma

Colorectal Cancer

Study ID

NCT07553572

Start date

Apr 14, 2026

Status verified date

Apr, 2026

Completion date

Mar 31, 2027

Anticipated

Primary completion date

Nov 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Age 18 years or older
2. Ability to understand English
3. About to begin definitive systemic treatment (or within 4 weeks of beginning treatment) based upon the oncology treatment intent form for a new diagnosis of breast cancer, colorectal cancer, or lymphoma.
4. Expected treatment duration of at least 12 weeks
5. Own or willing to receive a smartphone

Exclusion Criteria:

1. Cognitive impairment that would interfere with ability to use smartphone application (as assessed by their attending physician)
2. Visual or motor impairment that would prevent smartphone use
3. Expected survival less than 3 months

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: ASSIST phone application arm

The intervention consists of a smartphone-based application that provides personalized support using AI during cancer treatment. Patients will also receive standard care from their oncology team, including routine symptom management and supportive care measures.

no intervention: Usual Care

Patients in the usual care group will receive standard care from their oncology team, including routine symptom management and supportive care measures.

Interventions

ASSIST phone application

The intervention consists of a smartphone-based application that provides personalized support using AI during cancer treatment. Patients will also receive standard care from their oncology team, including routine symptom management and supportive care measures.

Primary outcome measure

  • Recruitment Rates [ Time Frame: From enrollment to end of intervention at 12 weeks ]
  • Percentage of participants using the digital application once per week in at least 7/12 weeks [ Time Frame: From enrollment to end of intervention at 12 weeks ]

Central Contacts and Locations

Central contacts

Patrick C Johnson, MD

6177244000pcjohnson@mgh.harvard.edu

Locations

Massachusetts General Hospital

Recruiting

Boston, Massachusetts, United States, 02114

Contacts

Patrick C Johnson, MD

6177244000pcjohnson@mgh.harvard.edu

More Information

Sponsor

Patrick C. Johnson, MD

Last update posted

Apr 28, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Patrick C. Johnson, MD on 2026-04-28.