Recruiting

High-Intensity Rehabilitation

Sponsor:

University of Alberta

Code:

NCT07553923

Conditions

Spinal Cord Injuries (SCI)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

High-intensity Rehabilitation

Usual Care

Study Details

Brief summary:

People with incomplete spinal cord injury (SCI) often have some preserved movement and may regain walking ability, but recovery can be limited, and more effective rehabilitation approaches are needed.The goal of this clinical trial is to learn if high-intensity walking rehabilitation can improve walking recovery and overall neurological recovery in individuals with subacute SCI. The investigators are also exploring the process of incorporating this type of physical therapy approach in an outpatient rehabilitation setting.

The main questions it aims to answer are:

  • Does high-intensity walking rehabilitation improve walking ability, compared to usual care for individuals with subacute spinal cord injury?
  • What are some of the barriers and facilitators to delivering high-intensity walking rehabilitation in an outpatient setting?

The investigators will compare usual care rehabilitation to a high-intensity rehabilitation program to see if higher-intensity physical therapy leads to better walking outcomes and improved recovery. The study will also explore how feasible it is to deliver this type of program in a real-world outpatient rehabilitation setting and gather perspectives from both participants and clinicians.

Participants will:

  • Attend regular outpatient physical therapy sessions focused on walking rehabilitation
  • Receive either usual care or a higher-intensity walking program delivered by their physical therapist
  • Have their activities, heart rate, step counts, and self-reported effort during therapy sessions monitored
  • Complete walking, balance, and neurophysiological assessments at the start and end of rehabilitation
  • Wear an activity monitor for one week at the beginning and end of the study to measure daily activity outside of therapy
  • Participants who receive the higher-intensity intervention may participate in an interview to share their experiences with rehabilitation

Conditions

Spinal Cord Injuries (SCI)

Study ID

NCT07553923

Start date

May 26, 2026

Status verified date

Jun, 2026

Completion date

Oct, 2027

Anticipated

Primary completion date

Oct, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adult (≥ 18 years of age)
  • Sustained a SCI within the past year
  • Motor incomplete SCI - classified as American Spinal Injury Association (ASIA) Impairment Scale levels C or D
  • Able to stand and initiate reciprocal steps through voluntary lower extremity movement but may require maximal physical assistance of at least one person and may include assistive devices (SWAT level 2A or above)
  • Indicate a walking-related goal on admission to outpatient physical therapy

Exclusion Criteria:

  • Medical or movement restriction(s) that limit high-intensity standing or walking rehabilitation (e.g., weight bearing restriction to lower extremities, cardiovascular constraints)
  • Inability to understand or communicate verbally in English

Study Design

Enrollment

25 participants

Anticipated

Allocation

Non randomized

Intervention Model

Sequential

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Usual Care

Participants will receive usual physical therapy intervention

experimental: High-intensity Rehabilitation

Participants will receive high-intensity physical therapy intervention

Interventions

High-intensity Rehabilitation

Participants will receive high-intensity physical therapy intervention

Usual Care

Usual care physical therapy

Primary outcome measure

  • Change from Baseline in the Ten Metre Walk Test [ Time Frame: Baseline and end of rehabilitation (up to 12 weeks following baseline) ]

Central Contacts and Locations

Central contacts

Caitlin Hurd, PhD

clhurd@ualberta.ca

Locations

Glenrose Rehabilitation Hospital

Recruiting

Edmonton, Alberta, Canada, T5G 0B7

Contacts

Caitlin Hurd, PhD

clhurd@ualberta.ca

More Information

Sponsor

University of Alberta

Last update posted

Jun 29, 2026

Last verified

Jun, 2026

Keywords

  • high-intensity
  • subacute
  • walking
  • physical therapy

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alberta on 2026-06-29.