Recruiting

Cardiac Diet

Sponsor:

Maya Guglin, MD

Code:

NCT07560592

Conditions

Heart Failure

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Normal Salt Diet

Cardiac Diet

Study Details

Brief summary:

The purpose of this study is to understand if low sodium (cardiac) diet is indeed necessary for better health outcomes in patients who suffered heart failure. This study will investigate the association between sodium intake and risk for 30-day re-admission in Heart Failure (HF) patients.

Conditions

Heart Failure

Study ID

NCT07560592

Start date

Jan 21, 2026

Status verified date

Apr, 2026

Completion date

Nov, 2028

Anticipated

Primary completion date

Nov 10, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Above 18 years of age
  • Hospitalization due to Heart Failure admitted within 24 hours

Exclusion Criteria:

  • Concomitant hypertension (blood pressure >150/90 mmHg on admission)
  • End stage renal disease (on hemodialysis or peritoneal dialysis
  • Cardiogenic shock

Study Design

Enrollment

500 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Normal Salt Diet

3-4 gm/day salt diet

placebo comparator: Cardiac Diet

2 gm/day salt diet

Interventions

Normal Salt Diet

This study will allow regular diet 3-4 g Na-Salt per day in patients with acute HF as an intervention, because the standard recommendation for such patients is cardiac diet with 2 g Na per day. The intervention will end when the patient is discharged from the hospital. They will follow routine clinical care recommendations after discharge from hospital.

Cardiac Diet

This arm of study will allow the cardiac diet with 2 g Na per day, that is standard recommendation for HF patients. They will follow routine clinical care recommendations after discharge from hospital.

Primary outcome measure

  • Length of hospital stay [ Time Frame: Hospital admission to time of discharge assessed up to 1 year ]
  • 30-day readmission [ Time Frame: 30 days after discharge from hospital after index event ]
  • NT-proBNP on discharge [ Time Frame: time of hospital admission to 30 days after discharge ]
  • Loop diuretic requirement during index admission [ Time Frame: time of hospital admission to 30 days after discharge ]

Central Contacts and Locations

Central contacts

Maya Guglin, MD

8483915776maya.guglin@rutgers.edu

Manisha Bajpai, PhD

manisha.bajpai@rutgers.edu

Locations

Robert Wood Johnson Barnabas Hospital - New Brunswick

Recruiting

New Brunswick, New Jersey, United States, 08901

Contacts

Maya Guglin, MD

8483915776maya.guglin@rutgers.edu

Manisha Bajpai, PhD

manisha.bajpai@rutgers.edu

More Information

Sponsor

Maya Guglin, MD

Last update posted

May 1, 2026

Last verified

Apr, 2026

Keywords

  • Heart failure, Salt diet

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Maya Guglin, MD on 2026-05-01.