Recruiting

Home Exercise Program

Sponsor:

University of Rochester

Code:

NCT07561034

Conditions

Pulmonary Hypertension

Interstitial Lung Disease

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Home Exercise Program, Aerobic Plus Strength Training

Home Exercise Program, Aerobic Only

Study Details

Brief summary:

This study evaluates the effects of a structured home exercise program in participants with pulmonary hypertension associated with interstitial lung disease. Participants will complete a defined exercise regimen over a 16-week period, and functional capacity and patient reported outcomes will be assessed at baseline and after the intervention. The study aims to determine whether a home-based exercise approach is feasible and associated with improvements in functional performance.

Conditions

Pulmonary Hypertension

Interstitial Lung Disease

Study ID

NCT07561034

Start date

Jul 15, 2026

Status verified date

Apr, 2026

Completion date

May 30, 2027

Anticipated

Primary completion date

May 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Follows at University of Rochester Medical Center Pulmonary Hypertension Clinic.
  • Adult patients (>18 years old) with right heart catheterization confirmed pulmonary hypertension interstitial lung disease on stable therapy dosing for at least 30 days.
  • Access to a smart phone or email to receive daily messages.
  • Clinically stable by the investigator.

Exclusion Criteria:

  • Pregnancy.
  • Pulmonary Hypertension Groups 1,2,4,5.
  • Resting tachycardia >120 beats/m during screening.
  • Inability to walk.
  • WHO Functional Class IV
  • Lack of access to email or text messaging.
  • Participating in a rehabilitation program.

Study Design

Enrollment

30 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Aerobic Plus Strength Training

Participants receive 16 weeks of structured daily exercise messages for aerobic and strength training activities with heart rate guidance. Participants also receive resistance bands and ankle weights.

active comparator: Aerobic only

Participants receive 16 weeks of structured daily aerobic exercise messages with heart rate guidance. Participants may perform walking or Cubii-based aerobic exercise.

Interventions

Home Exercise Program, Aerobic Plus Strength Training

Structured home based exercise program delivered by daily SMS text message or email for 16 weeks, including aerobic and strength training activities with heart rate guidance.

Home Exercise Program, Aerobic Only

Structured home based exercise program delivered by daily SMS text message or email for 16 weeks, including aerobic activities with heart rate guidance.

Primary outcome measure

  • Mean Change in Cardiac Effort From Baseline to 16 Weeks [ Time Frame: Baseline to 16 weeks ]

Central Contacts and Locations

Central contacts

Daniel Lachant, DO

585 273 4608Daniel_Lachant@urmc.rochester.edu

Locations

University of Rochester Medical Center

Recruiting

Rochester, New York, United States, 14642

Contacts

Daniel Lachant, DO

5852734608daniel_lachant@urmc.rochester.edu

Principal Investigator:

Daniel Lachant, DO

More Information

Sponsor

University of Rochester

Last update posted

Jul 24, 2026

Last verified

Apr, 2026

Keywords

  • Home Exercise
  • Exercise Therapy
  • PH-ILD

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Rochester on 2026-07-24.