Recruiting
Phase 3

Erector Spinae Plane Block

Sponsor:

UCLA

Code:

NCT07561827

Conditions

Adolescent Idiopathic Scoliosis (AIS)

Neuromuscular Scoliosis

Adolescent Idiopathic Scoliosis

Eligibility Criteria

Sex: All

Age: 10 - 18

Healthy Volunteers: Not accepted

Interventions

Ropivacaine Hydrocloride

Study Details

Brief summary:

This study is being done to better understand the efficacy of an erector spinae plane block (ESPB) in pain management for children with Adolescent Idiopathic Scoliosis or Neuromuscular Scoliosis undergoing Posterior Spinal Fusion surgery. The study team is trying to find out if receiving the ESPB leads to less pain and less need for pain medication after surgery.

The ESPB involves an injection of a local anesthetic, ropivacaine, into your child's back muscles to help block pain signals.

Conditions

Adolescent Idiopathic Scoliosis (AIS)

Neuromuscular Scoliosis

Adolescent Idiopathic Scoliosis

Study ID

NCT07561827

Start date

Jun 6, 2025

Status verified date

Apr, 2026

Completion date

Jan 26, 2027

Anticipated

Primary completion date

Jan 26, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 10 - 18

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Diagnosis of Adolescent Idiopathic Scoliosis (AIS) or neuromuscular scoliosis
  • Undergoing Posterior Spinal Fusion (PSF) Surgery

Exclusion Criteria:

  • Patients with forms of scoliosis other than AIS or NM Scoliosis.
  • Patients undergoing a spinal deformity correction surgery other than Posterior Spinal Fusion Surgery
  • Allergy or other contraindication to erector spinae plane block (ESPB) with Ropivacaine patients who are taking pre-operative opioids

Study Design

Enrollment

42 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: ESPB with Ropivacaine + standard postoperative pain protocol

Erector spinae plan block (ESPB) with Ropivacaine and standard postoperative pain protocol

no intervention: No ESPB + standard postoperative pain protocol

No erector spinae plane block (ESPB) or type of injection and standard posteropative pain protocol

Interventions

Ropivacaine Hydrocloride

This drug is approved as a local anesthetic.

Primary outcome measure

  • Compare Oral Morphine Equivalents and Benzodiazepine Doses used in the first 72 hours after surgery among patients who have a ESPB with standard postoperative pain protocols versus those with standard protocols alone. [ Time Frame: Change from Baseline to 72 hours after surgery. ]
  • Evaluate if combining ESPBs with standard postoperative pain protocols reduce postoperative pain scores in the first 24 hours postoperatively as compared to standard protocols alone. [ Time Frame: From Baseline to 24 hours after surgery. ]
  • Assess time to clearance from physical therapy among patients who have a ESPB with standard postoperative pain protocols versus those with standard protocols alone. [ Time Frame: From postoperative day 1 to physical therapy clearance. ]

Central Contacts and Locations

Central contacts

Tripta Rughwani

415-353-4701tripta.rughwani@ucsf.edu

Stephanie Chu

415-353-1454stephanie.chu4@ucsf.edu

Locations

University of California San Francisco

Recruiting

San Francisco, California, United States, 94158

Contacts

Tripta Rughwani

415-353-4701tripta.rughwani@ucsf.edu

Stephanie Chu

415-353-1454stephanie.chu4@ucsf.edu

Principal Investigator:

Ishaan Swarup, MD

More Information

Sponsor

University of California, San Francisco

Last update posted

May 1, 2026

Last verified

Apr, 2026

Keywords

  • posterior spinal fusion
  • pain management

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, San Francisco on 2026-05-01.