Recruiting

VevyeReal-World Assessment of VEVYE® for Short-Term Symptom and Sign Improvement of Dry Eye Disease in a Neuro-Ophthalmology Clinic: A 6-Month Prospective Observational Study

Sponsor:

Neuro-Ophthalmology of Texas

Code:

NCT07566975

Conditions

Dry Eye

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Cyclosporine ophthalmic solution 0.1%

Study Details

Brief summary:

patients from a Neuro Ophthalmology who have dry eye, some of which have neurotrophic keratitis are being analyzed after treatment with Vevye

Conditions

Dry Eye

Study ID

NCT07566975

Start date

Mar 31, 2026

Status verified date

Apr, 2026

Completion date

Nov 30, 2026

Anticipated

Primary completion date

Nov 30, 2026

Anticipated

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Age18 yr or older Diagnosis of neuro-ophthalmic condition Clinical diagnosis of dry eye disease OSDI score of 23 or greater at baseline Objective sign present Indicated for VEVYE prior to enrollment Ability and willingness to complete study visits and questionnaires

Exclusion Criteria:

Patients with a corneal ulcer Use of another cyclosporine or lifitegrast product within 30 days of baseline Ocular surgery within 30 prior to baseline Active ocular infection or severe ocular surface condition unrelated to DED Contact lens wearers ( must be off contacts for 30 days and the duration of trial) Any condition that prevents compliance or informed consent Subjects with severe scarring / zero sensitivity

Study Design

Enrollment

50 participants

Anticipated

Interventions and Outcome Measures

Arms

Dry Eye without neurotrophic changes

Dry Eye with neurotrophic changes

Interventions

Cyclosporine ophthalmic solution 0.1%

one drop in both eyes twice a day

Primary outcome measure

Corneal fluorescein staining [ Time Frame: Baseline compared to week 4 ]

Central Contacts and Locations

Central contacts

Laura Perez

12817238593 lperez@neuroeye.com

Rosa A Tang, MD

713-258-0009 lperez@neuroeye.com

Locations

Neuro Ophthalmology of TX

Recruiting

Houston, Texas, United States, 77074

Contacts

Laura Perez

2817238593 lperez@neuroeye.com

Rosa A Tang, MD

7132580009 rosatang.md@me.com

More Information

Sponsor

Neuro-Ophthalmology of Texas

Last update posted

May 5, 2026

Last verified

Apr, 2026

Keywords

Neurotrophic Keratitis
Dry Eye

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-14. This information was provided to ClinicalTrials.gov by Neuro-Ophthalmology of Texas on 2026-05-05.