Recruiting

HF-FOCUS

Sponsor:

Mayo Clinic

Code:

NCT07572955

Conditions

Acute Decompensated Heart Failure

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Lung Ultrasound

Study Details

Brief summary:

The purpose of this study is to examine shorter hospitalization length as well as a reduced rates of recurrent heart failure hospitalization compared to current standard of care in Acute Decompensated Heart Failure. A 1-day reduction in hospital length of stay in unblinded subjects receiving daily HF-FOCUS examinations compared to a blinded standard of care arm.

Conditions

Acute Decompensated Heart Failure

Study ID

NCT07572955

Start date

Aug 26, 2026

Status verified date

Sep, 2026

Completion date

Jun, 2028

Anticipated

Primary completion date

Jun, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Subjects ≥18 years of age
  • Admitted to St. Mary's Hospital Cardiology Progressive Care Unit (Cardiology 1-5 teams)
  • Admission diagnosis of either:

1. Acute systolic heart failure
2. Acute on chronic systolic heart failure
3. Acute diastolic heart failure
4. Acute on chronic diastolic heart failure
5. Acute right heart failure
6. Acute on chronic right heart failure
7. Failure heart biventricular
  • Able to provide informed consent and willing to undergo daily lung ultrasound examinations during their hospitalization.

Exclusion Criteria:

  • Subjects <18 years of age
  • Unable to provide informed consent.
  • Unwilling to undergo daily lung ultrasound examinations.

Study Design

Enrollment

500 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Diagnostic

Interventions and Outcome Measures

Arms

active comparator: Group 1

Patients undergoing daily lung ultrasound with the results reported to the provider care teams on admission and each morning

experimental: Group 2

Patients undergoing daily lung ultrasound but the results will be blinded to the provider care teams

Interventions

Lung Ultrasound

Patients will undergo lung ultrasound assessments at hospital admission, daily throughout admission, and at hospital discharge.

Primary outcome measure

  • Number of days in the hospital [ Time Frame: Baseline ]

Central Contacts and Locations

Central contacts

Andy Dang

507-255-7752dang.phong@mayo.edu

Locations

Mayo Clinic in Rochester

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

Andy Dang

507-255-7752dang.phong@mayo.edu

Principal Investigator:

Jared Bird, MD

More Information

Sponsor

Mayo Clinic

Last update posted

Sep 8, 2026

Last verified

Sep, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-09-08.