Recruiting

Observational Study

Sponsor:

Thomas Jefferson University

Code:

NCT07574645

Conditions

Spinal Dural Arteriovenous Fistula

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Given the lack of large multicenter datasets in the context of Spinal arteriovenous fistula, the strength of the evidence surrounding this rare disease is limited. SPIDER hence aims to address that by compiling patient-level data from centers all around the world.

Conditions

Spinal Dural Arteriovenous Fistula

Study ID

NCT07574645

Start date

Jan 5, 2026

Status verified date

May, 2026

Completion date

May, 2026

Anticipated

Primary completion date

May, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Type 1 spinal dural arteriovenous fistula, confirmed on imaging
  • Surgically or endovascularly treated
  • At least 1 available primary outcome

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Treatment success [ Time Frame: Recorded at the end of the embolization or surgery. ]
  • Recurrence [ Time Frame: Time-to-event Outcome Measures. Estimated period of time over which the event is assessed: on average 1.5 years after surgery. ]
  • Status of symptoms at last clinical follow-up [ Time Frame: Time-to-event Outcome Measures. Estimated period of time over which the event is assessed: on average 1.5 years after surgery. ]
  • Modified Aminoff-Logue Scale [ Time Frame: Time-to-event Outcome Measures. Estimated period of time over which the event is assessed: on average 1.5 years after surgery. ]
  • Modified Rankin Scale [ Time Frame: Time-to-event Outcome Measures. Estimated period of time over which the event is assessed: on average 1.5 years after surgery. ]
  • Mortality [ Time Frame: Time-to-event Outcome Measures. Estimated period of time over which the event is assessed: on average 1.5 years after surgery. ]

Central Contacts and Locations

Central contacts

Pascal Jabbour, MD

215-955-7000pascal.jabbour@jefferson.edu

Locations

Thomas Jefferson University Hospital

Recruiting

Philadelphia, Pennsylvania, United States, 19102

Contacts

Victor Gabriel El-Hajj, MD

215-955-7000victorgabriel.el-hajj2@jefferson.edu

More Information

Sponsor

Thomas Jefferson University

Last update posted

May 8, 2026

Last verified

May, 2026

Keywords

  • spinal dural arteriovenous fistula
  • spinal arteriovenous malformation
  • spinal AVF
  • sdAVF
  • international
  • multicenter
  • registry

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Thomas Jefferson University on 2026-05-08.