Recruiting

MILS

Sponsor:

Louisiana State University Health Sciences Center in New Orleans

Code:

NCT07576595

Conditions

Lung Cancer Screening

Tobacco Use Disorder

Smoking Cessation

Eligibility Criteria

Sex: All

Age: 50 - 70+

Healthy Volunteers: Not accepted

Interventions

Smoking cessation multilevel Intervention

Study Details

Brief summary:

This study aims to reduce disparities and the burden of lung cancer among African American smokers by supporting a Multiple-level intervention integrating lung cancer screening and smoking cessation (MILS), followed the NIH DEIA strategies using multilevel interventions that impact determinants of health and address health disparities at appropriate time points across the life course.

Conditions

Lung Cancer Screening

Tobacco Use Disorder

Smoking Cessation

Study ID

NCT07576595

Start date

Apr 17, 2025

Status verified date

Apr, 2026

Completion date

Jun, 2030

Anticipated

Primary completion date

Jun, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • African American
  • 20+ pack years of smoking
  • eligible for or received LDCT screening
  • current smoker
  • English speaking

Exclusion Criteria:

  • N/A

Study Design

Enrollment

250 participants

Anticipated

Allocation

Randomized

Intervention Model

Sequential

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

no intervention: Control

No intervention

experimental: Screening

LDCT lung cancer screening

Interventions

Smoking cessation multilevel Intervention

The intervention will utilize a multilevel intervention based on the Social Ecological Model's individual, institutional, and community levels.

Primary outcome measure

  • Stage of Change for Smoking Cessation [ Time Frame: Baseline, immediately post-intervention, and 6-month follow-up ]
  • 7-Day Point Prevalence Abstinence Rate [ Time Frame: Baseline, immediately post-intervention, and 6-month follow-up ]
  • 24-Hour Point Prevalence Abstinence Rate [ Time Frame: Baseline, immediately post-intervention, and 6-month follow-up ]
  • Daily Cigarette Consumption [ Time Frame: Baseline, immediately post-intervention, and 6-month follow-up ]
  • Nicotine Dependence (Fagerström Test for Nicotine Dependence) [ Time Frame: Baseline, immediately post-intervention, and 6-month follow-up ]

Central Contacts and Locations

Central contacts

Jessica Kassner, MS, MPH

504-568-5724jkassn@lsuhsc.edu

Locations

LSUHSC School of Public Health

Recruiting

New Orleans, Louisiana, United States, 70112

University Medical Center

Recruiting

New Orleans, Louisiana, United States, 70112

More Information

Sponsor

Louisiana State University Health Sciences Center in New Orleans

Last update posted

May 11, 2026

Last verified

Apr, 2026

Keywords

  • African American
  • Health Disparities
  • Lung Cancer Screening
  • Smoking Cessation
  • Tobacco Use
  • Low-Dose Computed Tomography
  • LDCT
  • Behavioral Intervention

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Louisiana State University Health Sciences Center in New Orleans on 2026-05-11.