Recruiting

Weight Regain Prevention

Sponsor:

University of Utah

Code:

NCT07577765

Conditions

Weight Loss

Weight Regain

Obesity & Overweight

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Interventions

Adaptive weight regain prevention

Study Details

Brief summary:

The purpose of this study is to develop and test an adaptive, individually tailored intervention to prevent weight regain in people who have intentionally lost weight. The main questions it aims to answer are:

  • Is an adaptive intervention with tailored re-engagement support feasible for individuals following intentional weight loss?
  • Does this intervention prevent weight regain after intentional weight loss?

Participants will:

  • Complete a baseline assessment of body measurements
  • Complete surveys on dietary intake, mental health, and physical activity

Participants will also engage in a 26-week program, which involves:

  • Receive regular educational texts/emails
  • Fill out weekly online survey check-ins
  • Weigh themselves at least weekly on a scale provided by the study
  • Some participants may receive health coaching during portions of the study.
  • Assessments will be repeated for all participants at the end of the intervention period.

Conditions

Weight Loss

Weight Regain

Obesity & Overweight

Study ID

NCT07577765

Start date

Jan 7, 2026

Status verified date

May, 2026

Completion date

Sep 1, 2027

Anticipated

Primary completion date

Sep 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Inclusion Criteria:

  • BMI of ≥ 27 prior to weight loss
  • Lost ≥ 7% of body mass in the past 6 months
  • Weight loss was intentional
  • No plans for weight loss surgery in the next 6 months
  • Access to a smart device that can download applications and receive text messages
  • Able to receive clearance for study participation from primary care provider

Exclusion Criteria:

  • Pregnant or within 12 months postpartum, or planning pregnancy
  • Uncontrolled conditions that affect overall health (cardiovascular, metabolic, renal, pulmonary, psychiatric, thyroid, cancers)
  • Food insecure
  • Bariatric surgery or cancer treatment within the past 5 years
  • Active or recent (<12 months) treatment/diagnosis of an eating disorder

Study Design

Enrollment

30 participants

Anticipated

Intervention Model

Single group

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Adaptive Intervention

Interventions

Adaptive weight regain prevention

Adaptive intervention that will tailor participant re-engagement with professional support (e.g. health coaches) based on behavioral triggers and anthropometric monitoring (diet changes, weight increase, failure to weigh weekly).

Primary outcome measure

  • Feasibility - Participant Retention [ Time Frame: From enrollment to the end of the 26-week monitoring period ]
  • Feasibility - Participant Adherence [ Time Frame: From enrollment to the end of the 26-week monitoring period ]
  • Efficacy - Participant Weight [ Time Frame: From enrollment to the end of the 26-week monitoring period ]
  • Efficacy - Participant Dietary Intake [ Time Frame: From enrollment to the end of the 26-week monitoring period ]
  • Efficacy - Eating Self-Efficacy in High-Risk Situations [ Time Frame: From enrollment to the end of the 26-week monitoring period ]
  • Efficacy - Eating Behavior Patterns [ Time Frame: From enrollment to the end of the 26-week monitoring period ]
  • Efficacy - Sleep/Rest Duration [ Time Frame: From enrollment to the end of the 26-week monitoring period ]
  • Efficacy - Daily Step Count [ Time Frame: From enrollment to the end of the 26-week monitoring period ]
  • Efficacy - Sedentary Behavior (Sitting/Lying Time) [ Time Frame: From enrollment to the end of the 26-week monitoring period ]
  • Efficacy - Standing Time [ Time Frame: From enrollment to the end of the 26-week monitoring period ]

Central Contacts and Locations

Central contacts

Josh Oliver

971-645-6693joshua.oliver@hsc.utah.edu

Locations

University of Utah

Recruiting

Salt Lake City, Utah, United States, 84112

Contacts

Josh Oliver

971-645-6693joshua.oliver@hsc.utah.edu

Principal Investigator:

Tanya Halliday, RD, PhD

More Information

Sponsor

University of Utah

Last update posted

May 11, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-07. This information was provided to ClinicalTrials.gov by University of Utah on 2026-05-11.