Recruiting

Advanced Therapy

Sponsor:

CorEvitas

Code:

NCT07615712

Conditions

Psoriasis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Observational (Non-Interventional) Registry

Study Details

Brief summary:

This is a 16-week prospective, single-arm cohort, study of patients initiating advanced therapy for the treatment of moderate-to-severe plaque PSO. Eligible patients must be willing to be seen in-person by their treating physician for a Baseline visit (with first dose of the advanced therapy occurring within 14 days), and at 2 (+/- 5 days), 4 (+/- 5 days), and 16 weeks (+14 days) calculated based on date of first dose of the advanced therapy and must provide informed consent prior to enrolling in the study or completing study-specific questionnaires or procedures. Data will be collected from both subjects and their treating dermatology provider at predetermined scheduled intervals (Baseline, Week 2, Week 4, and Week 16) using a structured and standardized data collection tool.

Conditions

Psoriasis

Study ID

NCT07615712

Start date

Apr 30, 2025

Status verified date

Aug, 2026

Completion date

Dec, 2035

Anticipated

Primary completion date

Dec, 2035

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

The inclusion criteria for this study will be as follows:

1. Patient is at least 18 years of age at the time of study enrollment
2. Patient has a diagnosis of moderate to severe plaque psoriasis based on an Investigator Global Assessment (IGA, part of routine care) score of 3 or 4 at the time of Enrollment.
3. Patient is initiating new Eligible Medication for the first time for the treatment of PSO.
4. Patient is willing and able to provide informed consent to participate in this study.
5. Patient is willing to be seen in-person by their treating dermatology provider at two (2), four (4), and sixteen (16) weeks following initiation of the advanced therapy.

Exclusion Criteria:

An individual who meets any of the following criteria will be excluded from participation in the study:

1. Patient is participating in a blinded clinical trial.
2. Patients that do not receive at least 1 dose of the advanced therapy within 14 days following the Enrollment/Baseline visit for the study.
3. Patients cannot be concurrently enrolled in both the CorEvitas PSO Registry and the CorEvitas Psoriasis (PSO) Rapid Response Non-Interventional Study.

A. Patients currently enrolled in the CorEvitas PSO Registry are ineligible for participation in the CorEvitas Psoriasis (PSO) Rapid Response Non-Interventional Study.

B. Patients otherwise meeting eligibility criteria can be enrolled in the CorEvitas Psoriasis (PSO) Rapid Response Non-Interventional Study C. Following completion or at time of Exit from the CorEvitas Psoriasis (PSO) Rapid Response Non Interventional Study, patients will be eligible to enroll into the CorEvitas PSO Registry for long term follow up at the standard of care cadence supported by the registry. A separate Informed consent will be obtained.

Study Design

Enrollment

2500 participants

Anticipated

Interventions and Outcome Measures

Interventions

Observational (Non-Interventional) Registry

This is an observational (non-interventional) registry

Primary outcome measure

  • Creation of a cohort of psoriasis subjects [ Time Frame: Baseline (Day 0), Week 2, 4 and 16 weeks after initiation of advanced therapy ]

Central Contacts and Locations

Central contacts

Psoriasis Rapid Response Study Team

6178655932ppd_corepsoriasis@thermofisher.com

Locations

CorEvitas, LLC

Recruiting

Waltham, Massachusetts, United States, 02451

Contacts

More Information

Sponsor

CorEvitas

Last update posted

Aug 26, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by CorEvitas on 2026-08-26.