Recruiting

InTune

Sponsor:

dōTERRA International

Code:

NCT07623811

Conditions

Healthy

Eligibility Criteria

Sex: All

Age: 18 - 64

Healthy Volunteers: Accepted

Interventions

Placebo

Cognitive Support System

Study Details

Brief summary:

This study will evaluate whether the InTune product system may help support attention, memory, focus, and other thinking skills in healthy adults ages 18-64. Participants will be randomly assigned to receive either the InTune products or placebo products that look and feel the same but do not contain active ingredients. Participants will use the products throughout their participation in the study and complete a series of cognitive tests and questionnaires at the beginning and end of the study. Researchers will compare changes in memory performance, self-reported mental clarity and focus, product experiences, and any side effects between the two groups.

Conditions

Healthy

Study ID

NCT07623811

Start date

Jun 10, 2026

Status verified date

Sep, 2026

Completion date

Dec 10, 2026

Anticipated

Primary completion date

Dec 10, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 64

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Able to read and understand English, willing to attend one study visit at the doTERRA campus in Pleasant Grove, UT

Exclusion Criteria:

  • Regular use (topical, aromatic, or internal) of rosemary, copaiba, cedarwood, peppermint, wild orange, Spanish sage, lime peel, marjoram, litsea, agarwood, vetiver, hiba wood, elderberry extract, or vanilla essential oil in the past month
  • Allergy or sensitivity to rosemary, copaiba, cedarwood, peppermint, wild orange, Spanish sage, lime peel, marjoram, litsea, agarwood, vetiver, hiba wood, elderberry extract, or vanilla essential oil
  • Use of recreational drugs within the past month
  • Color blindness
  • Pregnancy, either currently or within the last 3 months
  • Participation in a clinical trial within the past 30 days
  • Medical conditions, medications, or allergies that could compromise safety or data integrity, as determined by the medical reviewer or principal investigator

Study Design

Enrollment

100 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: InTune system

Aromatic use will entail breathing from a passive nasal aroma stick several times during cognitive testing, as directed by the survey and study staff. The aroma stick will contain 5 drops of InTune essential oil blend on a cotton wick inside a hard plastic casing with a lid.

Topical use will entail applying a solid stick to inner arms and chest directly before daily cognitive training. The stick includes a moisturizing base and 25% InTune essential oil blend plus hiba wood oil and elderberry extract. Placebo is the moisturizing base only.

placebo comparator: Placebo

Aromatic use will entail breathing from a passive nasal aroma stick several times during cognitive testing, as directed by the survey and study staff. The placebo aroma stick will contain 5 drops of benzaldehyde diluted to 1% in fractionated coconut oil on a cotton wick inside a hard plastic casing with a lid.

Topical use will entail applying a solid stick to inner arms and chest directly before daily cognitive training. The stick is a moisturizing base (similar to deodorant).

Interventions

Placebo

Aromatic use will entail breathing from a passive nasal aroma stick several times during cognitive testing, as directed by the survey and study staff. The placebo aroma stick will contain 5 drops of benzaldehyde diluted to 1% in fractionated coconut oil on a cotton wick inside a hard plastic casing with a lid. Topical use will entail applying a solid stick to inner arms and chest directly before daily cognitive training. The stick is a moisturizing base (similar to deodorant).

Cognitive Support System

InTune is a product system including an essential oil blend and active botanicals delivered in a liquid form for aromatic application and a solid stick for topical application. Aromatic use will entail breathing from a passive nasal aroma stick several times during cognitive testing, as directed by the survey and study staff. The aroma stick will contain 5 drops of InTune essential oil blend on a cotton wick inside a hard plastic casing with a lid. Topical use will entail applying a solid stick to inner arms and chest directly before daily cognitive training. The stick includes a moisturizing base and 25% InTune essential oil blend plus hiba wood oil and elderberry extract. Placebo is the moisturizing base only.

Primary outcome measure

  • Composite Z-Score [ Time Frame: 1 study visit, 90 minutes ]

Central Contacts and Locations

Central contacts

Nicole Stevens, PhD

8016522822clinicalresearch@pmhclinics.com

Locations

dōTERRA International

Recruiting

Pleasant Grove, Utah, United States, 84020

Contacts

Nicole Stevens, PhD

8016522822clinicalresearch@pmhclinics.com

More Information

Sponsor

dōTERRA International

Last update posted

Sep 4, 2026

Last verified

Sep, 2026

Keywords

  • neural plasticity
  • executive function
  • working memory
  • Immediate and Delayed Recall
  • Raven's Matrices
  • PROMIS Cognitive Scale

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by dōTERRA International on 2026-09-04.