Recruiting

Resistance-Training & Creatine

Sponsor:

University of Saskatchewan

Code:

NCT07625202

Conditions

Sarcopenia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Dietary supplementation during a 12 week resistance-training program (creatine)

Dietary supplementation during a 12 week resistance-training program (placebo)

Study Details

Brief summary:

GLP-1 receptor agonists are effective for weight loss, but significant muscle mass is lost as a proportion of this weight loss. This study combines resistance-training and creatine supplementation to try to prevent this loss of muscle mass.

Conditions

Sarcopenia

Study ID

NCT07625202

Start date

May 25, 2026

Status verified date

May, 2026

Completion date

Dec 31, 2027

Anticipated

Primary completion date

May 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Starting GLP-1 agonist therapy
  • 18 years of age or older

Exclusion Criteria:

  • Positive answers to a screening questionnaire for physical activity safety (the Get Active Questionnaire)

Study Design

Enrollment

40 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Creatine

10 grams per day creatine

placebo comparator: Placebo

Placebo (maltodextrin)

Interventions

Dietary supplementation during a 12 week resistance-training program (creatine)

creatine supplementation

Dietary supplementation during a 12 week resistance-training program (placebo)

Placebo

Primary outcome measure

  • Change in sit to stand performance (number of times) [ Time Frame: 12 weeks ]

Central Contacts and Locations

Central contacts

Philip D Chilibeck, PhD

306-966-1072phil.chilibeck@usask.ca

Locations

University of Saskatchewan

Recruiting

Saskatoon, SK - Saskatchewan, Canada, S7N 5B2

Contacts

Philip D Chilibeck, PhD

306-966-1072phil.chilibeck@usask.ca

More Information

Sponsor

University of Saskatchewan

Last update posted

Jun 4, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Saskatchewan on 2026-06-04.