Recruiting

Observational Study

Sponsor:

NIH

Code:

NCT07647549

Conditions

Pulmonary Hypertension

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Background:

Pulmonary hypertension (PH) is high blood pressure in the blood vessels of the lungs. It can lead to heart failure and death if not treated. Researchers want to create a repository of blood samples and health information collected from people with PH. They hope to use this information to find better ways to diagnose and treat PH.

Objective:

To collect blood samples and health information from people suspected of or diagnosed with PH.

Eligibility:

People aged 18 years and older who have or may have PH.

Design:

Researchers will collect information from participants medical records.

Participants will have blood drawn from a vein. About 3 tablespoons will be collected during the study visit. The visit will last about 1 hour.

Participants may choose to provide new blood samples at follow-up visits. Updated medical information may also be collected.

Participants may continue to participate as long as the study is ongoing. Participants may opt out of providing new blood samples but remain in the study.

All study samples will be stored at the National Institutes of Health. Health information will be stored in secure databases.

Conditions

Pulmonary Hypertension

Study ID

NCT07647549

Start date

Oct 26, 2026

Status verified date

Oct 19, 2026

Completion date

Jun 1, 2036

Anticipated

Primary completion date

Jun 1, 2036

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

  • INCLUSION CRITERIA:
  • Provision of signed and dated informed consent form
  • Males and females aged >=18 years old
  • Suspected of or diagnosed with PH
  • Able to understand and willing to sign a written informed consent document

EXCLUSION CRITERIA:

Any individual who does not meet all inclusion criteria or is deemed by the local investigator not to be a blood draw candidate will be excluded from participating in this study.

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Arms

Group 1 (suspected of or diagnosed)

Pulmonary Arterial Hypertension, PAH

Group 2 (suspected of or diagnosed)

PH due to left heart disease

Group 3 (suspected of or diagnosed)

PH due to lung diseases and/or hypoxia

Group 4 (suspected of or diagnosed)

PH due to thromboembolic disease

Group 5 (suspected of or diagnosed)

PH with unclear or multifactorial mechanisms

Primary outcome measure

  • Develop a multi-center biorepository. [ Time Frame: 10 years ]

Central Contacts and Locations

Central contacts

Michael A Solomon, M.D.

(301) 496-9320msolomon@cc.nih.gov

Locations

National Institutes of Health Clinical Center

Recruiting

Bethesda, Maryland, United States, 20892

Contacts

NIH Clinical Center Office of Patient Recruitment (OPR)

800-411-1222ccopr@nih.gov

More Information

Sponsor

National Institutes of Health Clinical Center (CC)

Last update posted

Oct 21, 2026

Last verified

Oct 19, 2026

Keywords

  • Pulmonary Hypertension
  • Biorepository

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-22. This information was provided to ClinicalTrials.gov by National Institutes of Health Clinical Center (CC) on 2026-10-21. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.