Recruiting

Red Panax Ginseng

Sponsor:

Arizona State University

Code:

NCT07648316

Conditions

Mental Acuity

Eligibility Criteria

Sex: All

Age: 18 - 30

Healthy Volunteers: Accepted

Interventions

Ginseng

Placebo

Study Details

Brief summary:

College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being. Neurological functions such as working memory, attention regulation, executive control, and emotional processing are highly sensitive to stressors, leaving young adults vulnerable to daily fluctuations in cognitive efficiency. Recent findings from the Healthy Minds Network (2025) indicate that although rates of moderate to severe depression among college students declined from 44% in 2022 to 37% in 2025, and anxiety symptoms fell from 37% to 32%, levels of psychological flourishing also dropped, falling to 36% despite these improvements.

Ginseng contains bioactive compounds known as ginsenosides that favorably influence brain function and inflammatory cascades. Studies in stressed and moderately stressed adults demonstrated reduced perceived stress, improved emotional processing, enhanced cognitive performance, and beneficial changes to biomarkers with ginseng supplementation. In addition, randomized controlled trials reported improvements in mood regulation, fatigue resistance, and aspects of working memory and attention following short-term ginseng supplementation. This study will examine the effects of daily red panax ginseng supplementation (3000 mg/day; two 1500 mg Red Panax gummies) on cognitive performance and emotional well-being in healthy young adults.

Conditions

Mental Acuity

Study ID

NCT07648316

Start date

Jun 22, 2026

Status verified date

Jun, 2026

Completion date

Jun 15, 2027

Anticipated

Primary completion date

Dec 15, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 30

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Healthy young adults
  • 18-30 years of age

Exclusion Criteria:

  • medication/drug use that has not been consistent for the previous 3 months or will be discontinued during the trial
  • unresolved chronic medical conditions (e.g., presence of persistent symptomology)
  • diagnosed clinical depression
  • acute illness
  • regular use of cigarettes or marijuana
  • pregnant or lactating women
  • not fluent in English
  • currently competing in sports or unusually high-intensity exercise protocols (e.g., high-intensity exercise greater than 30 minutes most days of the week)
  • current use of ginseng or adaptogenic supplements, or allergy to ginseng
  • any significant food allergies
  • not willing to attend two in-person lab visits in downtown Phoenix and follow study protocol (including abstaining from caffeine in the 12 hours prior to testing)

Study Design

Enrollment

30 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: ginseng

ginseng

placebo comparator: Placebo

strawberry gummy (2)

Interventions

Ginseng

This study will test the efficacy of ginseng on health compared to placebo treatment.

Placebo

This study will test the efficacy of ginseng on health compared to placebo treatment.

Primary outcome measure

  • cognitive performance [ Time Frame: 2 hours post ingestion ]
  • cognitive performance [ Time Frame: 2 weeks ]

Central Contacts and Locations

Central contacts

Locations

Health North ASU Downtown Campus

Recruiting

Phoenix, Arizona, United States, 85004

Contacts

More Information

Sponsor

Arizona State University

Last update posted

Nov 6, 2026

Last verified

Jun, 2026

Keywords

  • ginseng
  • mental health
  • cognitive performancd

Trial information was received from ClinicalTrials.gov and was last updated on 2026-11-07. This information was provided to ClinicalTrials.gov by Arizona State University on 2026-11-06. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.