Recruiting

Medical Imaging

Sponsor:

University of Minnesota

Code:

NCT07649031

Conditions

Fanconi Anemia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MRIs

Study Details

Brief summary:

This study being done to learn more about the use of medical Magnetic Resonance Imaging (mMRI) and dedicated dental MRI (ddMRI) as a non-invasive diagnosing tool when evaluating potential oral cancerous and precancerous lesions in Fanconi Anemia patients.

Conditions

Fanconi Anemia

Study ID

NCT07649031

Start date

Jun 23, 2026

Status verified date

Jun, 2026

Completion date

May 31, 2030

Anticipated

Primary completion date

May 31, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients with a diagnosis of Fanconi Anemia who are willing to participate and willing to have MRIs
  • Willing to provide informed consent

Exclusion Criteria:

  • Patient without diagnosis of FA
  • Patients with FA who are under the age of 18
  • Unable to tolerate any MRI due to claustrophobia
  • Any contraindication for the MRI
  • Unable to provide informed consent or comply with the study protocol

Study Design

Enrollment

80 participants

Anticipated

Interventions and Outcome Measures

Arms

FA patients with a history of HNSCC

This group will receive both mMRI and ddMRI, with an exam, every 3-4 months for 2 years (up to 16 scan (+exam) visits).

FA patients with no history of HNSCC

This group will receive two scans each of mMRI and ddMRI, with an exam, one year apart (up to 4 scan (+exam) visits).

Interventions

MRIs

mMRI and ddMRI

Primary outcome measure

  • sensitivity of mMRI and ddMRI in identifying dysplastic and malignant lesions in FA patients. [ Time Frame: Immediately after MRI ]
  • specificity of mMRI and ddMRI in identifying dysplastic and malignant lesions in FA patients. [ Time Frame: Immediately after MRI ]

Central Contacts and Locations

Central contacts

Carla Campbell, BS

612-625-6976camp2757@umn.edu

Locations

University of Minnesota

Recruiting

Minneapolis, Minnesota, United States, 55455

Contacts

Carla Campbell, BS

612-625-6976camp2757@umn.edu

More Information

Sponsor

University of Minnesota

Last update posted

Jul 2, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-11. This information was provided to ClinicalTrials.gov by University of Minnesota on 2026-07-02. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.