Sponsor:
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Code:
NCT07654374
Conditions
Obesity
Overweight
Chronic Weight Management
Type2 Diabetes Mellitus
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Accepted
Interventions
aleniglipron
aleniglipron
aleniglipron
Placebo
Brief summary:
Conditions
Obesity
Overweight
Chronic Weight Management
Type2 Diabetes Mellitus
Study ID
NCT07654374
Start date
Jul 17, 2026
Status verified date
Jun, 2026
Completion date
Nov, 2028
Anticipated
Primary completion date
Sep, 2028
Anticipated
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Accepted
Enrollment
1100 participants
Anticipated
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary purpose
Treatment
Arms
experimental: aleniglipron Arm 1
experimental: aleniglipron Arm 2
experimental: aleniglipron Arm 3
placebo comparator: Placebo Arm 4
Interventions
aleniglipron
aleniglipron
aleniglipron
Placebo
Primary outcome measure
Central contacts
Locations
ACCOMPLISH-2 Research Site
Recruiting
Birmingham, Alabama, United States, 35242
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Chandler, Arizona, United States, 85225
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Phoenix, Arizona, United States, 85028
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Sun City West, Arizona, United States, 85375
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Tucson, Arizona, United States, 85741
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Fountain Valley, California, United States, 92708
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
La Jolla, California, United States, 92123
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Rolling Hills Estates, California, United States, 90274
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
San Diego, California, United States, 92108
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Waterbury, Connecticut, United States, 06708
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Clearwater, Florida, United States, 33756
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Fort Myers, Florida, United States, 33912
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Jacksonville, Florida, United States, 32216
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Leesburg, Florida, United States, 34748
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Ocala, Florida, United States, 34470
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Ocoee, Florida, United States, 34761
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Atlanta, Georgia, United States, 30329
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Lawrenceville, Georgia, United States, 30046
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Union City, Georgia, United States, 30291
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Woodstock, Georgia, United States, 30189
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Meridian, Idaho, United States, 83646
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Des Moines, Iowa, United States, 50314
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Wichita, Kansas, United States, 67218
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Silver Spring, Maryland, United States, 20901
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Methuen, Massachusetts, United States, 01844
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Mankato, Minnesota, United States, 56001
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Minneapolis, Minnesota, United States, 55423
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Gulfport, Mississippi, United States, 39503
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Ridgeland, Mississippi, United States, 39157
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Chesterfield, Missouri, United States, 63005
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
City of Saint Peters, Missouri, United States, 63303
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Hazelwood, Missouri, United States, 63042
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Springfield, Missouri, United States, 65807
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
St Louis, Missouri, United States, 63141
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Missoula, Montana, United States, 59804
ACCOMPLISH-2 Research Site
Recruiting
The Bronx, New York, United States, 10455
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Charlotte, North Carolina, United States, 28210
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Fayetteville, North Carolina, United States, 28304
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Morehead City, North Carolina, United States, 23730
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Winston-Salem, North Carolina, United States, 27104
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Columbus, Ohio, United States, 43213
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Moore, Oklahoma, United States, 73160
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Tulsa, Oklahoma, United States, 74133
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Yukon, Oklahoma, United States, 73099
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Portland, Oregon, United States, 97202
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Philadelphia, Pennsylvania, United States, 19152
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Greer, South Carolina, United States, 29651
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Nashville, Tennessee, United States, 37203
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Austin, Texas, United States, 78704
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Farmers Branch, Texas, United States, 75234
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Houston, Texas, United States, 77040
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Houston, Texas, United States, 77054
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
San Antonio, Texas, United States, 78229
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Wylie, Texas, United States, 75098
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Manassas, Virginia, United States, 20110
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Suffolk, Virginia, United States, 23435
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comACCOMPLISH-2 Research Site
Recruiting
Renton, Washington, United States, 98057
Contacts
Medical Director
GSBRClinicalTrials@structuretx.comSponsor
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Last update posted
Oct 20, 2026
Last verified
Jun, 2026
Keywords
Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-23. This information was provided to ClinicalTrials.gov by Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics on 2026-10-20. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.