Recruiting

InSTILL

Sponsor:

Massachusetts General Hospital

Code:

NCT07655232

Conditions

Nursing Home Resident

Skilled Nursing Facility

Depression

Feasibility Studies

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Interventions for Stressful Transitions in Later Life (InSTILL) for Individuals

Study Details

Brief summary:

The goal of this clinical trial is to test a behavioral health program (Interventions for Stressful Transitions in Later Life, InSTILL, for Individuals) for skilled nursing facility residents. The main questions it aims to answer is whether the program is program is feasible, satisfactory, and helpful. Participants will join 6 bi-weekly sessions of the InSTILL program. Participants will complete assessments at three timepoints (all) and a brief-exit interview.

Conditions

Nursing Home Resident

Skilled Nursing Facility

Depression

Feasibility Studies

Study ID

NCT07655232

Start date

Nov 17, 2025

Status verified date

Oct, 2026

Completion date

Feb 28, 2027

Anticipated

Primary completion date

Jan 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Psychological distress, as indicated by a score Patient Health Questionnaire- 2 ≥ 2 OR Patient Health Questionnaire-9 ≥ 5
  • 5+ chronic conditions based on Elixhauser Comorbidity Index
  • Aged ≥ 18 years
  • Able and willing to participate in the study

Exclusion Criteria:

  • Intended length of SNF stay < 7 days
  • More than mild cognitive impairment, as indicted by Brief Interview for Mental Status (BIMS) <13
  • Participant's roommate is already enrolled in study/intervention
  • High risk of suicide/active documented SI per the PHQ-9, item 9 or otherwise
  • Participation in newly initiated psychotherapy

Study Design

Enrollment

20 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: InSTILL for Individuals

Participants in this arm will participate in the Interventions for Stressful Transitions in Later Life (InSTILL), a behavioral health intervention tailored to the needs of short stay nursing facility residents. InSTILL for Individuals includes 6 sessions (2x per week for about 3 weeks) delivered in person or remotely.

Interventions

Interventions for Stressful Transitions in Later Life (InSTILL) for Individuals

The Interventions for Stressful Transitions in Later Life (InSTILL) intervention is for skilled nursing facility residents experiencing elevated levels of psychological distress. The intervention is designed to improve life management skills and emotion regulation skill with the goal of reducing depression symptoms.

Primary outcome measure

  • Mean Total Score Treatment Credibility [ Time Frame: After session 1 of intervention, an average of 1 week after baseline ]
  • Mean Total Score Client Satisfaction Questionnaire [ Time Frame: Post intervention, an average of 4 weeks after baseline ]
  • Percentage of Eligible Participants Enrolled [ Time Frame: Post intervention, an average of 4 weeks after baseline ]
  • Percentage of Participants with Missing Data [ Time Frame: 4 weeks after post-intervention ]
  • Attendance Rate [ Time Frame: Post intervention, an average of 4 weeks after baseline ]
  • Clinician Fidelity [ Time Frame: Post intervention, an average of 4 weeks after baseline ]
  • Number of Adverse Events [ Time Frame: 4 weeks after post-intervention ]
  • Treatment Acceptability Survey [ Time Frame: Post intervention, an average of 4 weeks after baseline ]
  • Percentage of Participants Meeting Participant Comprehension Criterion [ Time Frame: Post intervention, an average of 4 weeks after baseline ]

Central Contacts and Locations

Central contacts

BRISK Study Coordinator

617-643-9406brisk@mgb.org

Locations

Massachusetts General Hospital

Recruiting

Boston, Massachusetts, United States, 02114

Contacts

BRISK Study Coordinator

617-643-9406brisk@mgb.org

More Information

Sponsor

Massachusetts General Hospital

Last update posted

Oct 20, 2026

Last verified

Oct, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-24. This information was provided to ClinicalTrials.gov by Massachusetts General Hospital on 2026-10-20. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.