Recruiting

Tele-CPASS & CPASS

Sponsor:

University of Texas, El Paso

Code:

NCT07661849

Conditions

Stroke

Hemiparesis

Upper Extremity Impairments

Stroke Rehabilitation

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Not accepted

Interventions

Tele-CPASS

In-person CPASS therapy

Study Details

Brief summary:

This study evaluates whether a home-based telerehabilitation program (tele-CPASS) is as effective as an in-person rehabilitation program (CPASS) for improving arm and hand function after stroke. Stroke often leads to long-term difficulty using the affected arm in daily activities, and access to in-person therapy can be limited. This study aims to determine whether therapy delivered remotely can provide similar benefits to standard in-clinic care.

Participants who recently experienced a stroke will be randomly assigned to receive 20 hours of upper extremity rehabilitation therapy either in person or through a telehealth platform. Both groups will receive the same type and amount of therapy focused on practicing meaningful, patient-selected daily activities. Participants will complete assessments before treatment, immediately after treatment, and at 6 and 12 months to measure recovery of arm function, real-world arm use, and participation in daily life.

The results of this study will help determine whether telerehabilitation can improve access to effective stroke recovery interventions while maintaining clinical effectiveness comparable to in-person therapy.

Conditions

Stroke

Hemiparesis

Upper Extremity Impairments

Stroke Rehabilitation

Study ID

NCT07661849

Start date

Sep 1, 2025

Status verified date

Jun, 2026

Completion date

Aug 31, 2029

Anticipated

Primary completion date

Aug 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age 21 years or older
  • Neuroimaging-confirmed stroke within 40 days prior to enrollment
  • Persistent hemiparesis resulting in impaired upper extremity function, defined by a score of 0 to 3 on the NIH Stroke Scale motor arm item
  • Able to participate in all study-related activities, including 1-year follow-up
  • Short Blessed Memory Orientation and Concentration Scale score less than 8
  • Able to follow 2-step commands
  • Montreal Cognitive Assessment (MoCA) score greater than 25
  • No upper extremity injury or condition that limited upper extremity use prior to the stroke

Exclusion Criteria:

  • Inability to provide informed consent
  • Persistent disabling neurologic condition, such as multiple sclerosis, Parkinsonism, amyotrophic lateral sclerosis, or dementia requiring medication
  • Clinically significant fluctuations in mental status within 72 hours prior to randomization
  • Active psychosis, psychosis within the prior 2 years, active substance abuse, or prior substance abuse
  • Dense sensory loss, defined by a score of 3 or 4 on the NIH Stroke Scale sensory item
  • Ataxia out of proportion to weakness in the affected arm, defined by a score greater than 1 on the NIH Stroke Scale ataxia item
  • Not expected to survive 12 months because of other illnesses
  • Pregnancy
  • Severe aphasia
  • Receipt of botulinum toxin or expectation of receiving botulinum toxin during the study period

Study Design

Enrollment

42 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Tele-CPASS

Participants receive 20 hours of therapist-guided upper extremity motor rehabilitation delivered remotely in the home using a telehealth platform. Therapy is individualized based on participant-prioritized activities and focuses on repetitive practice of meaningful daily tasks to improve arm and hand function after stroke.

active comparator: In-person CPASS

Participants receive 20 hours of therapist-guided upper extremity motor rehabilitation delivered in person in the clinic. Therapy is individualized based on participant-prioritized activities and focuses on repetitive practice of meaningful daily tasks to improve arm and hand function after stroke.

Interventions

Tele-CPASS

Intervention 1: Tele-CPASS Tele-CPASS is a home-based telerehabilitation intervention consisting of 20 hours of therapist-guided, task-specific upper extremity motor training delivered remotely using a telehealth platform for individuals with stroke. Therapy is individualized based on participant-selected functional goals and focuses on repetitive practice of meaningful daily activities to improve arm and hand function after stroke. Participants complete sessions in their home environment with real-time therapist guidance and may be provided with equipment and technology needed to support remote delivery.

In-person CPASS therapy

Intervention 2: In-person CPASS therapy In-person CPASS is a clinic-based rehabilitation intervention consisting of 20 hours of therapist-guided, task-specific upper extremity motor training delivered face-to-face. Therapy is individualized based on participant-selected functional goals and focuses on repetitive practice of meaningful daily activities to improve arm and hand function after stroke. Sessions are conducted in a clinical setting under direct supervision of a therapist.

Primary outcome measure

  • Upper Extremity Motor Function (Action Research Arm Test [ARAT]) [ Time Frame: Baseline, 3 months, 6 months, and 12 months ]

Central Contacts and Locations

Central contacts

Dr. Shashwati Geed, PT, PhD

915-747-7289sgeed@utep.edu

Locations

Rehabilitation Sciences Complex, University of Texas at El Paso, 3333 N Mesa St, El Paso, TX 79902

Recruiting

El Paso, Texas, United States, 79902

Contacts

Shashwati Geed, PhD

915-747-7289sgeed@utep.edu

Texas Tech University Health Sciences Center El Paso - Neurology Clinic

Recruiting

El Paso, Texas, United States, 79905

Contacts

Dr. Paisith Piriyawat, Medical Director, Rehabilitation Services, UMC-EP, MD

915-215-5900Paisith.Piriyawat@ttuhsc.edu

Israel Alba, MBA, CCRP

915-215-4616

University Medical Center of El Paso - Rehabilitation Services

Recruiting

El Paso, Texas, United States, 79905

Contacts

Dr. Paisith Piriyawat, Medical Director, Rehabilitation Services, UMC-EP, MD

915-215-5900Paisith.Piriyawat@ttuhsc.edu

More Information

Sponsor

University of Texas, El Paso

Last update posted

Jun 22, 2026

Last verified

Jun, 2026

Keywords

  • Telerehabilitation
  • Telehealth
  • Stroke rehabilitation
  • Upper extremity recovery
  • Motor recovery
  • Critical period plasticity
  • Wearable sensors
  • Accelerometry

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Texas, El Paso on 2026-06-22.