Recruiting

Observational Study

Sponsor:

City of Hope Medical Center

Code:

NCT07664579

Conditions

Anatomic Stage IV Breast Cancer AJCC v8

Glioblastoma

Lung Carcinoma

Malignant Solid Neoplasm

Metastatic Breast Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Non-Interventional Study

Study Details

Brief summary:

This study evaluates how useful and acceptable the components of the "Couples Coping Together Against Cancer", referred to as "The Program", are to the participants with cancer.

Conditions

Anatomic Stage IV Breast Cancer AJCC v8

Glioblastoma

Lung Carcinoma

Malignant Solid Neoplasm

Metastatic Breast Carcinoma

Study ID

NCT07664579

Start date

Jul 5, 2024

Status verified date

Jun, 2026

Completion date

Nov 16, 2026

Anticipated

Primary completion date

Nov 16, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Have received a diagnosis of a primary brain tumor (glioblastoma), or other cancers (breast, lung, etc.)
  • Are new patients to City of Hope (COH) (all sites) or receive at least some of their care at City of Hope- Duarte Campus (care is defined as: procedures, consults, laboratories, imaging, surgery, and/or treatment)
  • The patient is in a committed relationship/partnership with a partner and the partner is available and willing to participate
  • Are English or Spanish speaking
  • ≥ 18 years of age
  • Have access to a smartphone, computer/laptop or internet connection to complete all study procedures

Exclusion Criteria:

  • Significant cognitive impairment
  • Inpatient psychiatric treatment for severe mental illness or overt signs of severe psychopathology (e.g., psychosis)
  • Visual, hearing, voice, or motor impairment that prevents completion of study procedures as evidenced by clinical judgment
  • Committed partners will be excluded from the study if they:

  • Refuse to complete informed consent
  • Have cognitive impairment
  • Have severe mental illness that would prevent informed consent and completion of study activities as evidenced by clinical judgment

Study Design

Enrollment

160 participants

Anticipated

Interventions and Outcome Measures

Arms

Observational

Patient and partners receive access to the Connecting Care App tool and undergo biopsychosocial screening and psychoeducation sessions over 30-45 minutes and complete surveys on study. Patients and partners may also receive counseling sessions over 30-45 minutes for up to 4 sessions on study.

Interventions

Non-Interventional Study

Non-interventional study

Primary outcome measure

  • Accrual rate (AR) [ Time Frame: Up to 12 months ]
  • Retention rate (RR) [ Time Frame: At 3 month and 6 month follow up ]
  • Adherence rate (AdR) [ Time Frame: Up to 3 month follow up ]
  • Study Satisfaction (SS) [ Time Frame: Up to 6 month follow up ]

Central Contacts and Locations

Locations

City of Hope Medical Center

Recruiting

Duarte, California, United States, 91010

Contacts

William Dale

626-256-4673wdale@coh.org

Principal Investigator:

William Dale

More Information

Sponsor

City of Hope Medical Center

Last update posted

Jun 24, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by City of Hope Medical Center on 2026-06-24.