Recruiting

Laryngoscope Blades

Sponsor:

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Code:

NCT07667010

Conditions

Obstetric

Cesarean Birth

Airway Anesthesia

Intubation

General Anesthesia; Tracheal Intubation

Eligibility Criteria

Sex: Female

Age: 0+

Healthy Volunteers: Not accepted

Interventions

Macintosh Style Blade

Hyperangulated blade

Study Details

Brief summary:

Cesarean section under general anesthesia requires intubation (insertion of a tube through the mouth into the breathing pipe to support breathing during the surgery). A device called a video laryngoscope is used, which has a smooth, curved, or less curved component called 'a blade' that helps the doctor gently see the voice box and guide the breathing tube safely into place during anesthesia; it is not a sharp tool blade.

There are two types of video laryngoscopes blades: a Macintosh- style blade with a gentle curve, approximately 90 degrees) and a hyperangulated blade (with a more pronounced curve).

Although video laryngoscopes are safe and both types have been used for around 20 years, it is not known whether one type works better that the other in patients undergoing cesarean delivery under general anesthesia. Because general anesthesia is used in only a small proportion (about 5%) of all cesarean deliveries, research in this area is limited.

The main purpose of the study is to assess if a study comparing these two types of blades in the obstetric population is feasible. This is also known as a feasibility study, which aims to test the study plan and determine whether enough participants will join a larger study and accept the study procedures. The results will be used as a guide for a larger study.

Conditions

Obstetric

Cesarean Birth

Airway Anesthesia

Intubation

General Anesthesia; Tracheal Intubation

Study ID

NCT07667010

Start date

Jun 22, 2026

Status verified date

Jun, 2026

Completion date

Jun 30, 2028

Anticipated

Primary completion date

Jan 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1\. Pregnant patients undergoing emergency or urgent cesarean delivery under general anesthesia requiring tracheal intubation.

Exclusion Criteria:

1. No tracheal intubation performed and (ii) patient refusal of consent.
2. Patients not receiving general anesthesia.
3. Patients that previously participated in the study.

Study Design

Enrollment

100 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

active comparator: Macintosh style blade

Study patients in this arm will be intubated using a Macintosh style blade

active comparator: Hyperangulated blade

Study patients in this arm will be intubated using a Hyperangulated style blade

Interventions

Macintosh Style Blade

Macintosh- style blade with a gentle curve, approximately 90 degrees

Hyperangulated blade

hyperangulated blade (with a more pronounced curve

Primary outcome measure

  • Patient Enrollment [ Time Frame: 3 days ]
  • Intervention Adherence [ Time Frame: 3 days ]
  • Data Completeness [ Time Frame: 3 days ]

Central Contacts and Locations

Central contacts

Locations

Mount Sinai Hospital

Recruiting

Toronto, Ontario, Canada, M5G 1X5

Contacts

Principal Investigator:

Fabricio Zasso, MD

More Information

Sponsor

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Last update posted

Oct 28, 2026

Last verified

Jun, 2026

Keywords

  • obstetric
  • obstetric anesthesia
  • intubation
  • airway safety in OB patients
  • video laryngoscopy
  • cesarean delivery
  • general anesthesia in cesarean delivery
  • macintosh blade
  • hyperangulated blade
  • intubation in OB patients
  • general anesthesia

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-29. This information was provided to ClinicalTrials.gov by Samuel Lunenfeld Research Institute, Mount Sinai Hospital on 2026-10-28. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.