Recruiting

Mifepristone & Misoprostol

Sponsor:

UCLA

Code:

NCT07671989

Conditions

Menstrual Regulation

Menstrual Health Intervention

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Accepted

Interventions

Mifepristone + Misoprostol

Study Details

Brief summary:

The Period Pills Study is a prospective observational study among people who decide to use a combination of mifepristone and misoprostol for menstrual regulation.

Conditions

Menstrual Regulation

Menstrual Health Intervention

Study ID

NCT07671989

Start date

Jun 22, 2026

Status verified date

Aug, 2026

Completion date

May 31, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Be 18 years old or older
  • Read and speak English
  • Know the date of their last menstrual period within 2 days
  • Have a period that is late by up to 21 days
  • Must have had regular periods in the last 4 months
  • Does not want to be pregnant
  • Does not want to verify pregnancy status
  • Understand that if they are pregnant, the pills will end their pregnancy
  • Does not have contraindications to mifepristone and misoprostol (Risk factors for ectopic pregnancy; history of bleeding disorder or anticoagulant therapy; history of chronic adrenal failure, long-term corticosteroid therapy; allergy to mifepristone/misoprostol/prostaglandins; history of hemorrhagic disorders or anticoagulant therapy; history of inherited porphyrias; has an IUD; currently use a contraceptive implant or injectable)

Exclusion Criteria:

  • Under 18 years old
  • Does not read and speak English
  • Does not know the date of their last menstrual period within 2 days
  • Has not had regular periods in the last 4 months
  • Wants to be pregnant
  • Wants to verify pregnancy status
  • Does not display understanding that if they are pregnant, the pills will end their pregnancy
  • Has any contraindications to mifepristone and misoprostol (Risk factors for ectopic pregnancy; history of bleeding disorder or anticoagulant therapy; history of chronic adrenal failure, long-term corticosteroid therapy; allergy to mifepristone/misoprostol/prostaglandins; history of hemorrhagic disorders or anticoagulant therapy; history of inherited porphyrias; has an IUD; currently use a contraceptive implant or injectable)

Study Design

Enrollment

100 participants

Anticipated

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Study Participants

Study participants will be persons who have late period of up to 21 days

Interventions

Mifepristone + Misoprostol

Study participants are given mifepristone and misoprostol for menstrual regulation.

Primary outcome measure

  • Interest in period pills [ Time Frame: Documented at Enrollment Survey ]
  • Satisfaction with period pills [ Time Frame: Documented at Follow-up Survey, 4 weeks after drug administration ]

Central Contacts and Locations

Central contacts

Ushma D Upadhyay, PhD, MPH

415-353-4626ushma.upadhyay@ucsf.edu

Jennifer Ko, MLIS

415-353-9113jennifer.ko@ucsf.edu

Locations

Roanoke Health Center

Recruiting

Roanoke, Virginia, United States, 24017

Contacts

Christine Hernández, MPH, MPM, CPHQ

828-280-5723christina.hernandez@ppsat.org

Matthew Zerden, MD, MPH

617-935-2394matthew.zerden@ppsat.org

More Information

Sponsor

University of California, San Francisco

Last update posted

Sep 2, 2026

Last verified

Aug, 2026

Keywords

  • late period
  • missed period
  • mestruation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, San Francisco on 2026-09-02.