Recruiting
Phase 2

uMAT-R & Engagement

Sponsor:

Washington University School of Medicine

Code:

NCT07673380

Conditions

Opioid Use

Stimulant Use

Depression and Anxiety Symptoms

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

uMAT-R + enhanced community engagement

Original uMAT-R supplementary mHealth recovery intervention

Study Details

Brief summary:

The sequential trial compares recovery and mHealth engagement outcomes among Black participants who participated in the mHealth intervention uMAT-R or uMAT-R + enhanced community engagement. The mHealth intervention seeks to support people in various stages of recovery who are also seeking other forms of substance use treatment. Participants are recruited from community-based substance use treatment facilities and recovery services. Participants must be adults who have or are currently using opioids and/or stimulants.

Conditions

Opioid Use

Stimulant Use

Depression and Anxiety Symptoms

Study ID

NCT07673380

Start date

Aug 31, 2025

Status verified date

Jun, 2026

Completion date

Feb 28, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Have a history of opioid and/or stimulant use
  • Identify as Black and/or African American
  • Seek treatment at local substance use treatment centers
  • Fluent in English
  • U.S. resident
  • 18 years of age or older at the time of data collection.

Exclusion Criteria:

  • Self-reported cognitive impairment that would limit ability to participate in research.

Study Design

Enrollment

300 participants

Anticipated

Allocation

Non randomized

Intervention Model

Sequential

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: uMAT-R + enhanced community engagement

uMAT-R + enhanced community engagement involves an optimized community engagement strategy employed by the intervention team.

active comparator: Original uMAT-R supplementary mHealth recovery intervention

uMAT-R supplementary mHealth recovery intervention is the original intervention disseminated without optimization of the community engagement approach.

Interventions

uMAT-R + enhanced community engagement

uMAT-R + enhanced community engagement involves an optimized community engagement strategy employed by the intervention team. This involves in-person interactions with eligible participants and recruitment sites.

Original uMAT-R supplementary mHealth recovery intervention

uMAT-R supplementary mHealth recovery intervention is the original intervention without optimization of the community engagement approach.

Primary outcome measure

  • Abstinence/ Changes in Substance Use [ Time Frame: Time 0 (Baseline) and Time 1 (One Month) ]
  • Opioid use/ Stimulant use disorder symptoms [ Time Frame: Time 0 (Baseline) and Time 1 (One Month) ]

Central Contacts and Locations

Central contacts

Hannah Szlyk

917-836-4225szlyk@wustl.edu

Elecia Worley

e.m.worley@wustl.edu

Locations

Washington University School of Medicine

Recruiting

St Louis, Missouri, United States, 63110

Contacts

Hannah Szlyk, PhD

917-836-4225szlyk@wustl.edu

More Information

Sponsor

Washington University School of Medicine

Last update posted

Jun 29, 2026

Last verified

Jun, 2026

Keywords

  • Digital health
  • Community engagement

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Washington University School of Medicine on 2026-06-29.