Recruiting

Tai Chi/Qigong

Sponsor:

Arizona State University

Code:

NCT07675681

Conditions

Implementation Science

Women Health

Disability Physical

Meditation

Tai Chi

Eligibility Criteria

Sex: Female

Age: 35 - 64

Healthy Volunteers: Not accepted

Interventions

Accesible Tai Chi/Qigong (TCQ)

Health Education Videos (HEV)

Study Details

Brief summary:

REVIVE is a randomized controlled trial designed to evaluate the effects of a remotely delivered seated Tai Chi/Qigong (TCQ) intervention on cardiometabolic health, stress, sleep, and psychological well-being among women with mobility impairments.

Women with mobility impairments experience higher rates of obesity, cardiometabolic disease, chronic stress, sleep disturbances, and mental health concerns compared with women without disabilities. Limited access to accessible physical activity programs and barriers to participation in traditional exercise interventions contribute to these health disparities. Tai Chi and Qigong are gentle mind-body practices that may improve physical and psychological health through movement, breathing, and mindfulness techniques and can be adapted for individuals with limited mobility.

Participants will be randomized to either a seated Tai Chi/Qigong intervention or a health education video control condition. During the 12-week intervention phase, participants will receive daily video-based content delivered remotely. Participants assigned to the Tai Chi/Qigong group will engage in seated meditative movement practices, while participants assigned to the control group will receive health and wellness education videos unrelated to physical activity or nutrition behavior change.

Outcomes will be assessed remotely at baseline, post-intervention, and follow-up. Primary outcomes include waist circumference and indicators of physiological stress regulation, including heart rate variability and salivary cortisol. Secondary outcomes include perceived stress, emotion regulation, depression, anxiety, emotional eating, sleep quality, and sleep disturbance. Additional measures collected through wearable technology, sleep diaries, questionnaires, and biological samples will be used to examine potential behavioral, psychological, and physiological mechanisms underlying intervention effects.

The findings from this study will contribute to the development of accessible, scalable, and evidence-based health promotion interventions designed to improve cardiometabolic health and overall well-being among women with mobility impairments.

Conditions

Implementation Science

Women Health

Disability Physical

Meditation

Tai Chi

Study ID

NCT07675681

Start date

Sep 1, 2026

Status verified date

Aug, 2026

Completion date

Aug 30, 2030

Anticipated

Primary completion date

Aug 30, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 35 - 64

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Self-identify as a woman.
  • Age 35-64 years.
  • Mobility impairment lasting at least 1 year.
  • Regular use of a mobility aid (e.g., wheelchair, scooter, walker, cane, crutches, or other assistive device).
  • Community dwelling.
  • Able to demonstrate sufficient upper-extremity mobility to participate in seated Tai Chi/Qigong activities.
  • Access to a smartphone, tablet, or computer with internet access.
  • Willing to wear a study-provided wearable device and complete study assessments.
  • Reside in the United States.
  • Waist circumference ≥ 33 inches (84 cm).
  • Perceived Stress Scale (PSS) score ≥ 15.
  • Insomnia Severity Index (ISI) score ≥ 8.
  • Emotional eating indicated by a score < 3 on the Mindful Eating Questionnaire (MEQ) Emotional Response subscale.
  • Able to understand written and spoken English.
  • Able to provide informed consent.
  • Able to provide healthcare provider approval for participation.

Exclusion Criteria:

  • Medical conditions that would make participation unsafe, as determined during screening.
  • Inability to safely perform seated upper-body movements.
  • Current participation in a structured Tai Chi, Qigong, or similar meditative movement program.
  • Pregnancy, lactation, or plans to become pregnant during the study period.
  • Cognitive, visual, auditory, or other impairments that would preclude completion of study procedures.
  • Implanted cardiac devices or implanted electronic devices that interfere with physiologic measurements.
  • Severe arrhythmia, left ventricular assist device (LVAD), or other conditions that interfere with heart rate variability assessment.
  • Use of sleep medications three or more times per week.
  • Medical conditions or medications that substantially affect autonomic nervous system activity, sleep, or stress-related outcomes.
  • Uncontrolled cardiovascular, neurological, psychiatric, or other serious medical conditions that would preclude safe participation.

Study Design

Enrollment

280 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Accesible Tai Chi/Qigong

Participants receive a 12-week remotely delivered seated Tai Chi/Qigong intervention consisting of daily video-based meditative movement sessions adapted for women with mobility impairments.

active comparator: Health Education Videos (HEV)

Participants receive a 12-week remotely delivered health education program consisting of daily video-based wellness education content on a variety of health-related topics.

Interventions

Accesible Tai Chi/Qigong (TCQ)

A remotely delivered seated Tai Chi/Qigong intervention designed for women with mobility impairments. Participants receive daily video-based sessions that incorporate seated meditative movement, breathing exercises, mindfulness, relaxation techniques, and body awareness practices. Short and long session options are available throughout the 12-week intervention period.

Health Education Videos (HEV)

A remotely delivered health education program consisting of daily video-based wellness education content provided over 12 weeks. Topics include healthy aging, preventive healthcare, chronic disease awareness, communication with healthcare providers, and other general wellness topics. The program does not include Tai Chi, Qigong, exercise instruction, or physical activity behavior change content.

Primary outcome measure

  • Waist Circumference (cm) [ Time Frame: Baseline (T1), Post-Intervention (T2, Week 15), and Follow-Up (T3, Week 29) ]
  • High-Frequency Heart Rate Variability (HF Power) [ Time Frame: Baseline 2-week assessment period, Week 15 (post-intervention) 2-week assessment period, and Week 29 (follow-up) 2-week assessment period. ]
  • Diurnal Salivary Cortisol Area Under the Curve (AUCg) [ Time Frame: Baseline (T1), Post-Intervention (T2, Week 15), and Follow-Up (T3, Week 29) ]

Central Contacts and Locations

Central contacts

Rebecca E Lee, PhD

6024960910releephd@yahoo.com

Locations

Arizona State University

Recruiting

Phoenix, Arizona, United States, 85004

Contacts

Rebecca E Lee, PhD

6024960910releephd@yahoo.com

Principal Investigator:

Rebecca E Lee, PhD

More Information

Sponsor

Arizona State University

Last update posted

Aug 5, 2026

Last verified

Aug, 2026

Keywords

  • Mobility Impairment
  • Tai Chi/Qigong
  • Cardiometabolic Health
  • Women with Disabilities
  • Stress Regulation
  • Sleep Health

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Arizona State University on 2026-08-05.