Recruiting

GLP-1RA & SGLTi

Sponsor:

Indiana University

Code:

NCT07676565

Conditions

Type 1 Diabetes

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

This will be a multicenter registry-based study to evaluate safety and efficacy of GLP-1RA and SGLTi therapies in adjunct to insulin in adults with type 1 diabetes (T1D) over 1 year. This study will enroll participants who have been prescribed adjunct therapy as part of usual care.

Conditions

Type 1 Diabetes

Study ID

NCT07676565

Start date

Mar 24, 2026

Status verified date

Jun, 2026

Completion date

Apr, 2028

Anticipated

Primary completion date

Apr, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adults ≥18 years of age
  • Clinical diagnosis of T1D
  • GLP-1RA or SGLTi (SGLT-1 and SGLT-2 inhibitors) drug prescribed by their provider for any indication as part of usual care with use for no more than 1 week
  • Use of CGM and availability of CGM data for 1 month prior to enrollment and expected to be available throughout the study
  • Willing and able to provide informed consent

Exclusion Criteria:

  • No exclusion criteria other than those not meeting inclusion criteria above

Study Design

Enrollment

300 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Change in HbA1c by type of therapy [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Kanchan Bhasin, MBBS

(317)-278-2752kanbhas@iu.edu

Locations

Hoag Memorial Hospital

Recruiting

Newport Beach, California, United States, 92663

Contacts

Brittany Dennis

949-764-6896Brittany.Dennis@hoag.org

Principal Investigator:

David Ahn, MD

Emory University

Recruiting

Atlanta, Georgia, United States, 30303

Contacts

sabeena usman

404-251-8959sabeena.usman@emory.edu

Principal Investigator:

Francisco Pasquel, MD

Northwestern University

Recruiting

Chicago, Illinois, United States, 60611

Contacts

Evelyn Fronczyk

312-908-9002evelyn.guevara@northwestern.edu

Principal Investigator:

Grazia Aleppo, MD

Maine Health Research Institute

Recruiting

Portland, Maine, United States, 04102

Contacts

Debra Burris

207-662-2467debra.burris@mainehealth.org

Principal Investigator:

Jay Ambalavanan, MD

Harvard Medical School

Recruiting

Boston, Massachusetts, United States, 02115

Contacts

Grace Ordonez

617-732-4245gordonez@bwh.harvard.edu

Principal Investigator:

Zeb Saeed, MD

Henry Ford Hospital

Recruiting

Detroit, Michigan, United States, 48202

Contacts

Lydia Oehring

313-916-3906loehrin1@hfhs.org

Principal Investigator:

Davida Kruger, ANP

Mount Sinai

Recruiting

New York, New York, United States, 10029

Contacts

Sophie Baun

212-241-4301sophie.baum@mssm.edu

Principal Investigator:

Carol Levy, MD

More Information

Sponsor

Indiana University

Last update posted

Jun 30, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-08. This information was provided to ClinicalTrials.gov by Indiana University on 2026-06-30. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.