Recruiting

Steri-Strips

Sponsor:

Riverside University Health System Medical Center

Code:

NCT07686913

Conditions

Cesarean Section

Surgical Site Infection

Wound Dehiscence

Seroma

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Steri-Strip™ Skin Closures

Standard Cesarean Wound Closure

Study Details

Brief summary:

This study is evaluating whether Steri-Strips® provide additional benefits when used after cesarean section (C-section) surgery. Steri-Strips are adhesive strips that are commonly placed over a surgical incision to provide support while the wound heals. At our hospital, Steri-Strips are routinely used after C-sections in addition to standard wound closure techniques, although they are not considered part of the standard recommended closure method.

Researchers want to determine whether adding Steri-Strips actually reduces wound complications such as infection, fluid collection under the skin, or reopening of the incision. Previous studies have shown mixed results, with some suggesting little difference in wound healing outcomes while others reported differences in scar appearance. Steri-Strips may also increase costs, add time to the surgery, and occasionally cause skin irritation or allergic reactions.

Participants in this study will be randomly assigned to one of two groups. One group will receive standard cesarean wound closure with Steri-Strips, while the other group will receive standard wound closure without Steri-Strips. Researchers will compare wound healing, complications, patient outcomes, and costs between the two groups.

The goal of this study is to determine whether Steri-Strips improve recovery after cesarean delivery and whether their routine use is beneficial and cost-effective. The findings may help guide future recommendations for cesarean wound care and improve outcomes for patients undergoing C-section delivery.

Conditions

Cesarean Section

Surgical Site Infection

Wound Dehiscence

Seroma

Study ID

NCT07686913

Start date

Jun, 2026

Status verified date

Jun, 2026

Completion date

Dec, 2027

Anticipated

Primary completion date

Jun, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Female patients age 18 years or older
  • Pregnant patients undergoing cesarean delivery at Riverside University Health System Medical Center (RUHS)
  • Able and willing to provide informed consent

Exclusion Criteria:

  • Known allergy or hypersensitivity to Steri-Strip™ materials or adhesives
  • Inability or unwillingness to provide informed consent
  • Anticipated inability to complete the 30-day postpartum follow-up evaluation

Study Design

Enrollment

610 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Standard Closure + Steri-Strips

Participants undergo standard cesarean skin closure followed by application of Steri-Strip™ skin closure strips according to a standardized study protocol.

active comparator: Standard Closure Alone

Participants undergo standard cesarean skin closure without application of Steri-Strip™ skin closure strips.

Interventions

Steri-Strip™ Skin Closures

Application of Steri-Strip adhesive skin closure strips following standard cesarean section wound closure according to a standardized protocol.

Standard Cesarean Wound Closure

Standard skin closure performed following cesarean delivery according to institutional practice.

Primary outcome measure

  • Incidence of Cesarean Section Wound Complications [ Time Frame: Within 30 days postpartum ]

Central Contacts and Locations

Central contacts

Locations

Riverside University Health System Medical Center

Recruiting

Moreno Valley, California, United States, 92555

Contacts

Matthew X Perera, DO, MS

8184800214mattpereraruhs@gmail.com

More Information

Sponsor

Riverside University Health System Medical Center

Last update posted

Jul 7, 2026

Last verified

Jun, 2026

Keywords

  • Cesarean Section
  • Cesarean Delivery
  • C-Section
  • Steri-Strips
  • Skin Closure
  • Wound Closure
  • Surgical Site Infection
  • Wound Dehiscence
  • Seroma
  • Postoperative Wound Complications
  • Obstetric Surgery
  • Incision Management
  • Surgical Wound Healing
  • Maternal Morbidity
  • Randomized Controlled Trial

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Riverside University Health System Medical Center on 2026-07-07.