Recruiting

Eye Focus

Sponsor:

Rochester Institute of Technology

Code:

NCT07691463

Conditions

Monochromatic

L- and S-cone Modulation Only

L- and M-cone Modulation Only

M and S-cone Modulation Only

Eligibility Criteria

Sex: All

Age: 0 - 35

Healthy Volunteers: Accepted

Interventions

Color

Study Details

Brief summary:

In this experiment, subjects will view shapes on a screen with varying colors and be asked to focus their eyes on the shapes. The shapes will look as though they are jumping to random distances away from the eye. As the subjects focus their eyes on the shapes, the investigators will measure the focus of their eyes using a device called a wavefront sensor. This device uses infrared light to measure the optical properties of the eye in real time. Our goal is to find out how well the eye focuses on different colors. Our broad goal is to better understand how the eye focuses because that process is a major part of having clear and good vision.

Conditions

Monochromatic

L- and S-cone Modulation Only

L- and M-cone Modulation Only

M and S-cone Modulation Only

Study ID

NCT07691463

Start date

Jul 2, 2026

Status verified date

Jul, 2026

Completion date

Dec 15, 2026

Anticipated

Primary completion date

Dec 15, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 35

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Between 18-35 years of age
  • Normal or corrected-to-normal (glasses/contact lenses) vision.

Exclusion Criteria:

  • Vision worse than 20/20 while wearing glasses / contact lenses.
  • Fragile or loose teeth (participants need to bite a piece of dental clay to stabilize their heads so that measurements can be taken from their eyes)
  • Current pregnancy (experiment requires sitting down without moving for stretches of time)
  • Heart disease
  • Personal/familial history of epilepsy

Study Design

Enrollment

20 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Color variation in visual stimulus

Each participant undergoes all experimental conditions, in a within-subjects design. Each intervention corresponds to a different stimulus color. The 4 colors are: 1) grayscale (L, M, and S-cone modulation), 2) L and S cone modulation only, 3) L and M cone modulation only, and 4) M and S cone modulation only.

Interventions

Color

Each intervention involves showing a participant a stimulus with a particular color on a screen display, and asking the participant to focus their eyes on the stimulus. The 4 colors are: 1) grayscale (L, M, and S-cone modulation), 2) L and S cone modulation only, 3) L and M cone modulation only, and 4) M and S cone modulation only.

Primary outcome measure

  • Accuracy of ocular accommodation [ Time Frame: Because this is a basic science experiment, each measurement takes place at the same time as the intervention. There will be two sessions, each lasting approximately 1 hour, on separate days (day 1 and day 2). ]
  • Speed of ocular accommodation [ Time Frame: Because this is a basic science experiment, each measurement takes place at the same time as the intervention. There will be two sessions, each lasting approximately 1 hour, on separate days (day 1 and day 2). ]

Central Contacts and Locations

Central contacts

Benjamin M Chin, Doctorate

8454534320bmccis@rit.edu

Locations

Chester F. Carlson Center for Imaging Science

Recruiting

Rochester, New York, United States, 14623

Contacts

Benjamin M Chin, Doctorate

8454534320bmccis@rit.edu

Principal Investigator:

Benjamin M Chin, Doctorate

More Information

Sponsor

Rochester Institute of Technology

Last update posted

Jul 17, 2026

Last verified

Jul, 2026

Keywords

  • Ocular accommodation
  • Visual acuity
  • Physiological optics
  • Visual psychophysics
  • Color science

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Rochester Institute of Technology on 2026-07-17.