Sponsor:
GlaxoSmithKline
Code:
NCT07701993
Conditions
Metabolic Dysfunction-associated Steatohepatitis
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Efimosfermin alfa
Placebo
Brief summary:
Conditions
Metabolic Dysfunction-associated Steatohepatitis
Study ID
NCT07701993
Start date
Jul 22, 2026
Status verified date
Sep, 2026
Completion date
Aug 24, 2033
Anticipated
Primary completion date
Jun 23, 2033
Anticipated
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Enrollment
1740 participants
Anticipated
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary purpose
Treatment
Arms
experimental: Participants receiving efimosfermin alfa
placebo comparator: Participants receiving placebo
Interventions
Efimosfermin alfa
Placebo
Primary outcome measure
Central contacts
Locations
GSK Investigational Site
Recruiting
Little Rock, Arkansas, United States, 72211
Contacts
Principal Investigator:
John Baber
GSK Investigational Site
Recruiting
Folsom, California, United States, 95630
Contacts
Principal Investigator:
Nazir Rahim
GSK Investigational Site
Recruiting
Miami, Florida, United States, 33135-4661
Contacts
Principal Investigator:
Yaneicy Gonzalez Rojas
GSK Investigational Site
Recruiting
Miami, Florida, United States, 33155
Contacts
Principal Investigator:
Jorge Amaya
GSK Investigational Site
Recruiting
Ocala, Florida, United States, 34471
Contacts
Principal Investigator:
Robert Barish
GSK Investigational Site
Recruiting
St Louis, Missouri, United States, 63141
Contacts
Principal Investigator:
Brian Mcmorrow
GSK Investigational Site
Recruiting
Arlington, Texas, United States, 76012
Contacts
Principal Investigator:
Reem Ghalib
GSK Investigational Site
Recruiting
Austin, Texas, United States, 78745-5675
Contacts
Principal Investigator:
Nomita Kim
GSK Investigational Site
Recruiting
Bellaire, Texas, United States, 77401
Contacts
Principal Investigator:
Everald Manning
GSK Investigational Site
Recruiting
Dallas, Texas, United States, 75243-1921
Contacts
Principal Investigator:
Valentine Ebuh
GSK Investigational Site
Recruiting
Humble, Texas, United States, 77346
Contacts
Principal Investigator:
Brian Chou
GSK Investigational Site
Recruiting
San Antonio, Texas, United States, 78209
Contacts
Principal Investigator:
Robert Morin Jr
GSK Investigational Site
Recruiting
San Antonio, Texas, United States, 78215
Contacts
Principal Investigator:
Eric Lawitz
Sponsor
GlaxoSmithKline
Last update posted
Sep 30, 2026
Last verified
Sep, 2026
Keywords
Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-23. This information was provided to ClinicalTrials.gov by GlaxoSmithKline on 2026-09-30. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.