Recruiting

Weight Loss Maintenance

Sponsor:

ORI Community and Evaluation Services

Code:

NCT07708064

Conditions

Overweight or Obesity

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Interventions

JITAI Combined with psychological intervention

Active Control

Study Details

Brief summary:

This trial will test the effectiveness of a weight loss maintenance intervention designed to help participants respond more adaptively to weight regain. Participants will be randomly assigned to one of two conditions. In one condition, participants will receive brief exercises (e.g., written reflections, videos) sent to through a smartphone app immediately after they regain weight or miss a weigh-in. These exercises will use mindfulness, acceptance, and self-compassion strategies to help participants stay motivated for their long term goals, even when weight regain feels demoralizing. In the comparison condition, participants will receive weekly reminders of standard weight control strategies strategies.

Conditions

Overweight or Obesity

Study ID

NCT07708064

Start date

Jul 14, 2026

Status verified date

Aug, 2026

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Ages 18-70 years
  • BMI of 25-50 kg/m2
  • Current weight is 3% lower than their highest weight in the past 3 years
  • Desire to maintain their weight or lose more
  • Ability to engage in PA, as defined as being able to walk two full city blocks without stopping
  • Smartphone and Internet access
  • Successful completion of all enrollment procedures
  • Ability to attend a workshop(s) on a Monday or Tuesday evening

Exclusion Criteria:

  • History of bariatric surgery
  • History of being diagnosed with an eating disorder
  • Currently pregnant, breastfeeding, or planning to become pregnant in the next 24 months
  • Enrolled in another formal weight loss/weight maintenance program
  • Currently taking a GLP-1 medication.

Study Design

Enrollment

120 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: JITAI Condition

Participants in this condition will receive a 6-month weight loss maintenance intervention that uses mindfulness, acceptance, and self-compassion strategies to respond to weight regain.

active comparator: Active Control Condition

Participants in this condition will receive minimal intervention designed to reflect "usual care" for weight loss maintenance.

Interventions

JITAI Combined with psychological intervention

For six months, participants will receive a just-in-time adaptive interventions via a smartphone app immediately after they gain weight or they skip a weigh-in (according to a specific algorithm). Interventions will engage participants in mindfulness, acceptance, and self-compassion-based (MASC) strategies through different modalities (e.g., writing exercises, videos, audio reflections). They will take approximately 1-10 minutes. Participants will also attend an introductory workshop, during which they will receive the instructions weigh daily, learn the importance of quickly responding to weight regain, and be introduced to MASC strategies. They will also attend two booster workshops during the 6-month period.

Active Control

For six months, participants will receive weekly, automated messages via a smartphone app with reminders of standard behavioral weight control principles. Participants will attend an introductory workshop, during which they will receive instructions to weigh daily and learn the importance of responding to weight regain.

Primary outcome measure

  • State negative affect [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • State shame [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • State Motivation [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • State Self-Efficacy [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • Current confidence in the effectiveness of weight control behaviors [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • State self-compassion [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • State mindfulness [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • State acceptance [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • Self-serving interpretation of weight gain [ Time Frame: Whenever participants regain weight during the 6 month study period ]
  • Daily Calorie Tracking (Yes/No) [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • Daily MVPA [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • Likelihood of weighing in the following day [ Time Frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period ]
  • Weight change [ Time Frame: End of treatment (6 months after baseline) ]
  • Intervention acceptability [ Time Frame: End of treatment (6 months after baseline) ]
  • Calorie Tracking Frequency [ Time Frame: 6 months (duration of study period) ]
  • Average Weekly MVPA [ Time Frame: 6 months (duration of study period) ]
  • Frequency of Weighing In [ Time Frame: 6 months (duration of study period) ]

Central Contacts and Locations

Central contacts

Charlotte Hagerman, PhD

14109372035chagerman@ori.org

Locations

Oregon Research Institute Community and Evaluation Services

Recruiting

Springfield, Oregon, United States, 97477

Contacts

Charlotte Hagerman, PhD

4109372035chagerman@ori.org

More Information

Sponsor

ORI Community and Evaluation Services

Last update posted

Aug 11, 2026

Last verified

Aug, 2026

Keywords

  • just-in-time adaptive interventions
  • weight regain
  • self-weighing
  • self-compassion
  • acceptance-based behavioral treatments
  • mindfulness
  • behavioral weight loss

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by ORI Community and Evaluation Services on 2026-08-11.