Recruiting

Knee Surgery Evaluation

Sponsor:

Angelina Vera MD

Code:

NCT07709819

Conditions

Meniscal Tears

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Nanoscopic Arthroscopy of the Knee

Study Details

Brief summary:

The goal of this clinical trial is to look at how well different surgeries heal over time in patients that have previously undergone arthroscopic knee interventions. These procedures may include cartilage repair or grafting, meniscus repair or trimming, ligament reconstruction, cartilage smoothing, and treatments such as amniotic tissue or platelet rich plasma (PRP).

Using a very small camera called a nanoarthroscope, doctors will take a "second look" inside the knee after surgery to see how it has healed. These findings will be compared to patient-reported outcomes, such as pain and function scores, as well as images taken during the original surgery.

The goal is to determine whether this second look provides useful information that can help guide recovery and future care.

Conditions

Meniscal Tears

Study ID

NCT07709819

Start date

May 20, 2026

Status verified date

Jul, 2026

Completion date

May 20, 2029

Anticipated

Primary completion date

May 20, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adults aged 18 years and older who have undergone or are scheduled to undergo arthroscopic knee intervention.
  • Eligible procedures include meniscus repair, biocartilage procedures, and other arthroscopic biologic interventions of the knee
  • Ability to understand and provide informed consent
  • Agreement to undergo postoperative in-clinic second-look nanoscopic arthroscopy of the knee.

Exclusion Criteria:

  • Refusal to undergo postoperative in-clinic second-look nanoscopic arthroscopy of the knee.
  • Inability to provide informed consent.
  • Individuals who are not yet adults (infants, children, teenagers).
  • Pregnant women
  • Prisoners

Study Design

Enrollment

15 participants

Anticipated

Intervention Model

Single group

Primary purpose

Diagnostic

Interventions and Outcome Measures

Arms

experimental: Postoperative Nanoscopic Knee Evaluation

Participants who consent will undergo an in-clinic postoperative nanoscopic arthroscopy of the knee at a routine follow-up visit. Images obtained during nanoscopic evaluation will be compared with preoperative MRI and intraoperative arthroscopic images to estimate healing and findings will be correlated with patient-reported outcome measures.

Interventions

Nanoscopic Arthroscopy of the Knee

Participants who agree to participate will undergo a postoperative in-clinic nanoscopic arthroscopy of the knee at a routine follow-up visit. A small nanoscope will be inserted into the knee joint in a clinic setting to obtain images that will be used for comparison to the arthroscopic images taken from their surgery and preoperative MRI images. The estimated healing will then be recorded and compared with patient reported outcome survey scores.

Primary outcome measure

  • Correlation between Estimated Percentage Meniscal Healing at Second Look Nanoscopic Arthroscopy and PROMIS Score. [ Time Frame: From baseline (preoperative assessment) to the postoperative second-look nanoscopic arthroscopy visit (3 to 24 months after the index meniscal repair procedure). ]

Central Contacts and Locations

Central contacts

Robert J Panganiban

(702) 383-7336robert.panganiban@umcsn.com

Robert Bimbi, PhD

(702) 383-7302robert.bimbi@umcsn.com

Locations

University Medical Center of Southern Nevada

Recruiting

Las Vegas, Nevada, United States, 89102

Contacts

Robert Panganiban

702-383-7336robert.panganiban@umcsn.com

Robert Bimbi, PhD

702-383-7302robert.bimbi@umcsn.com

Principal Investigator:

Angelina Vera, MD, FAAOS, FAANA

More Information

Sponsor

Angelina Vera MD

Last update posted

Jul 17, 2026

Last verified

Jul, 2026

Keywords

  • Cartilage Repair
  • Cartilage Grafting
  • Meniscus Repair
  • Meniscus Trimming
  • Ligament Reconstruction
  • Cartilage Smoothing
  • Nanoscope
  • Nanoscopic Diagnostic Arthroscopy
  • Knee Joint

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Angelina Vera MD on 2026-07-17.