Recruiting

Anti-Inflammatory Diet

Sponsor:

UCLA

Code:

NCT07713940

Conditions

Systemic Lupus Erthematosus (SLE)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

anti-inflammatory diet

Study Details

Brief summary:

To study the effect of anti-inflammatory diet on clinical and biological outcomes in lupus

Conditions

Systemic Lupus Erthematosus (SLE)

Study ID

NCT07713940

Start date

Jul 1, 2026

Status verified date

Jul, 2026

Completion date

Jul 1, 2029

Anticipated

Primary completion date

Jul 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • patients who meet the 2019 EULAR/ACR Classification Criteria for SLE
  • patients who are on Cellcept or Myfortic for at least 3 months prior to screening
  • patients with a score of ≥55 on the Patient Reported Outcomes Measurement Information System (PROMIS) Pain interference scale.

Exclusion Criteria:

  • pregnant or lactating patients,
  • patients with food allergy
  • patients on antibiotics within 4 weeks of the screening
  • patients that change the SLE therapy during the length of the study (12 weeks).

Study Design

Enrollment

36 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: anti-inflammatory diet

anti-inflammatory diet

Interventions

anti-inflammatory diet

anti-inflammatory diet for 6 weeks

Primary outcome measure

  • PROMIS pain interference [ Time Frame: 6 weeks ]
  • PROMIS fatigue [ Time Frame: 6 weeks ]

Central Contacts and Locations

Central contacts

Monica Guma, MD, PhD

858-822-6523mguma@health.ucsd.edu

Locations

Altman Clinical Translational Research Insitute (UC San Diego)

Recruiting

La Jolla, California, United States, 92097

Contacts

Monica Guma, MD, PhD

858-mguma@health.ucsd.edu

Principal Investigator:

Monica Guma, MD.PhD

More Information

Sponsor

University of California, San Diego

Last update posted

Jul 20, 2026

Last verified

Jul, 2026

Keywords

  • lupus
  • diet
  • anti-inflammatory diet
  • mediterranean diet
  • cellcept
  • mycophenalate
  • microbiome

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, San Diego on 2026-07-20.