Recruiting
Phase 1

BL1332

Sponsor:

Bausch & Lomb Incorporated

Code:

NCT07717918

Conditions

Healthy

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Interventions

BL1332 eye drops

BL1332 Placebo eye drops

Study Details

Brief summary:

Single center, double-masked study of BL1332 on Capsaicin-Induced Ocular Pain in Healthy Subjects

Conditions

Healthy

Study ID

NCT07717918

Start date

Jul 6, 2026

Status verified date

Jul, 2026

Completion date

Aug, 2026

Anticipated

Primary completion date

Aug, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Male or female ≥ 18 to ≤ 65 years of age.
  • In good health, as assessed at Screening by the Investigator from past medical history, physical examination (abbreviated), and laboratory tests.
  • Does not wear contact lenses, or is willing to refrain from wearing contact lenses for the duration of the study.

Exclusion Criteria:

  • Women of childbearing potential or non-vasectomized males with partners of childbearing potential are not eligible unless they are using an effective method of contraception and agree to use an effective method of contraception until at least 30 days after study treatment.
  • Any medical condition (systemic or ophthalmic) that may, in the opinion of the Investigator, preclude the safe administration of IP, safe participation in this study, or confound the assessment of safety or efficacy.
  • Unwilling or unable to comply with the study protocol.

Study Design

Enrollment

28 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: BL1332 eye drops

placebo comparator: BL1332 Placebo eye drops

Interventions

BL1332 eye drops

Taken 1 time

BL1332 Placebo eye drops

Taken 1 time

Primary outcome measure

  • Ocular pain severity assessed by numeric pain rating scale (NPRS) [ Time Frame: Assessed 5 seconds post-capsaicin dose ]

Central Contacts and Locations

Central contacts

Celia Busby

9453277624celia.busby@bausch.com

Locations

Site 101

Recruiting

Newport Beach, California, United States, 92663

More Information

Sponsor

Bausch & Lomb Incorporated

Last update posted

Jul 21, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Bausch & Lomb Incorporated on 2026-07-21.