Recruiting

MedMemos Intervention

Sponsor:

Nationwide Children's Hospital

Code:

NCT07718204

Conditions

Hematopoietic Cell Transplant

Eligibility Criteria

Sex: All

Age: 0 - 12

Healthy Volunteers: Not accepted

Interventions

MedMemos

Study Details

Brief summary:

The goal of this clinical trial is to test the MedMemos Intervention with parents and children who have received a bone marrow transplant. The main study questions are:

  • Is the MedMemos intervention acceptable to patients and families?
  • Is the MedMemos intervention feasible for patients, families, and healthcare providers?
  • Does MedMemos help patients and families take their medications better?

Participants will be asked to complete surveys, attend 4 intervention sessions, and use an electronic box or pill bottle to store their medications in.

Conditions

Hematopoietic Cell Transplant

Study ID

NCT07718204

Start date

May 1, 2026

Status verified date

Jul, 2026

Completion date

Dec 31, 2028

Anticipated

Primary completion date

Dec 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 12

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Child had a Pediatric Allogeneic Hematopoietic Cell Transplant (PAHCT)
  • Child is 0-12 years of age
  • At the time of recruitment child is still in the hospital for PAHCT
  • Child's primary caregiver is responsible for administering medical care and is willing to give consent to participate
  • Child is prescribed an oral medication regimen at discharge

Exclusion Criteria:

  • Caregiver does not speak English, Spanish, or Arabic
  • Caregiver is not available to provide written permission for the child's participation
  • EMR or medical team report of the caregiver's cognitive status precludes completion of questionnaires
  • The child's medical status or condition precludes completion of the study questionnaires as determined by the physician or caregiver
  • Caregiver is unwilling to store medication in an electronic monitor

Study Design

Enrollment

25 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: MedMemos

This arm will provide participants with the MedMemos Intervention

Interventions

MedMemos

MedMemos is a 4-session tailored adherence promotion intervention that will provide caregivers with a combination of tailored and standardized medication and adherence education videos and a "Medication Management Kit" that provides tailored strategies to target identified barriers to successful medication management.

Primary outcome measure

  • Intervention Acceptability [ Time Frame: At the end of session 4 (An average of 14 days following the patient's hospital discharge, up to 28 days following discharge) ]
  • Intervention Feasibility - Percentage of patients who enroll out of those approached [ Time Frame: Enrollment rate will be continually monitored throughout enrollment and final enrollment percentage will be calculated at the close of enrollment. Enrollment is estimated to end during Month 9 of Year 2. ]
  • Intervention Feasibility - Percentage of intervention sessions and follow-ups completed by enrolled participants. [ Time Frame: Completion rates will be calculated during the study in real time as part of study monitoring. Final study completion rates will be reported after the final follow-up is complete. Follow-ups are estimated to be complete Month 11 of Year 2. ]
  • Intervention Feasibility - Percentage of the intervention protocol delivered by the interventionist. [ Time Frame: Intervention fidelity will be monitored in real time to maintain adherence to the intervention protocol. Final intervention fidelity will be reported after the final MedMemos session is completed. Sessions are anticipated to end in Month 11 Year 2. ]

Central Contacts and Locations

Central contacts

Ahna LH Pai, PhD

(614) 938-1601Ahna.Pai@nationwidechildrens.org

Sarah N Drake, MS

(614) 259-7462sarah.drake2@nationwidechildrens.org

Locations

Nationwide Children's Hospital

Recruiting

Columbus, Ohio, United States, 43205

Contacts

Ahna LH Pai, PhD

(614) 938-1601Ahna.Pai@nationwidechildrens.org

Sarah N Drake, MS

(614) 259-7462sarah.drake2@nationwidechildrens.org

Principal Investigator:

Ahna LH Pai, PhD

More Information

Sponsor

Nationwide Children's Hospital

Last update posted

Jul 21, 2026

Last verified

Jul, 2026

Keywords

  • Hematopoietic Cell Transplantation
  • Bone Marrow Transplant
  • Pediatric
  • Cancer
  • Bone Marrow Failure
  • Adherence
  • Medication Adherence
  • Non-Adherence
  • Adherence Promotion Intervention
  • Immunosuppressant
  • Transition to Outpatient
  • Managing Medication Regimens
  • Child
  • Caregiver
  • Parent
  • GVHD
  • Infection

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Nationwide Children's Hospital on 2026-07-21.