Recruiting

Observational Study

Sponsor:

Brigham and Women's Hospital

Code:

NCT07719049

Conditions

Aging

Facial Aging

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The investigators aim to examine how FaceAge estimates (a measure of biological age based on facial features) change across different time points and identify factors that may influence these changes. This will help the investigators understand the consistency and reliability of the FaceAge algorithm and allow them to make improvements.

Conditions

Aging

Facial Aging

Study ID

NCT07719049

Start date

Oct 23, 2025

Status verified date

May, 2026

Completion date

Oct, 2027

Anticipated

Primary completion date

Oct, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • The protocol enrolls healthy volunteers from the adult (age 18 and above) general population. All races and genders will be included.

Exclusion Criteria:

  • Any skin condition or recent facial injury that could affect facial appearance.
  • Inability to follow study instructions or provide informed consent.
  • Taking new or strong medication on the day of image capture could potentially affect appearance or alertness.

Study Design

Enrollment

10000 participants

Anticipated

Interventions and Outcome Measures

Arms

Healthy volunteers

Individuals that are not currently/have never received care at any MGB affiliated institutions.

Primary outcome measure

  • FaceAge estimate(s) [ Time Frame: Up to three years from the date of enrollment. ]
  • Changes in FaceAge estimates [ Time Frame: Up to three years from the date of enrollment. ]

Central Contacts and Locations

Central contacts

Raymond Mak, MD

(617) 632-5734bwhfaceage@mgb.org

Locations

Brigham and Women's Hospital

Recruiting

Boston, Massachusetts, United States, 02115

Contacts

Andrew Warrington, BS

(617) 632-5734bwhfaceage@mgb.org

Fridolin Haugg, MS

(617) 632-5734bwhfaceage@mgb.org

More Information

Sponsor

Brigham and Women's Hospital

Last update posted

Aug 17, 2026

Last verified

May, 2026

Keywords

  • Artificial Intelligence
  • Aging
  • Biomarkers of Aging

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Brigham and Women's Hospital on 2026-08-17.