Recruiting

Neurodynamics

Sponsor:

High Point University

Code:

NCT07721220

Conditions

Sciatic Leg Pain

Hamstring Muscle Tightness

Hamstring Muscle Strain

Hamstring Muscle Strength

Hamstring Injuries

Eligibility Criteria

Sex: All

Age: 18 - 30

Healthy Volunteers: Accepted

Interventions

Sciatic Slider

Sciatic Tensioner

Mechanically loaded neurodynamic sciatic floss

Elastic Resistance Band

Study Details

Brief summary:

This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population. This study aims to find if these interventions can maintain or promote strength and endurance in the hamstrings. The studies results will help physical therapist better prescribe exercise and hands-on treatment for hamstring and sciatic nerve related conditions and injuries.

Conditions

Sciatic Leg Pain

Hamstring Muscle Tightness

Hamstring Muscle Strain

Hamstring Muscle Strength

Hamstring Injuries

Study ID

NCT07721220

Start date

Jun 15, 2026

Status verified date

Jul, 2026

Completion date

Jul, 2026

Anticipated

Primary completion date

Jul, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 30

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Participants must be between 18 and 30 years of age.
  • Must be able to read, understand, and provide informed consent, in English.
  • Must be currently participating in an organized sport (e.g. collegiate, club, or competitive recreational level) or engaging in structured resistance training and athletic conditioning for recreational sports events (e.g 5k, marathon, Crossfit, Hyrox, etc).
  • Medically stable with no known contraindications to physical exertion.
  • Cleared for participation in strength or maximal-effort isometric testing.
  • Be able to perform lower extremity isometric testing without pain that limits maximal effort.
  • Must have 2 lower extremities capable to producing full range knee flexion and extension range of motion.
  • No medical condition that significantly alters lower extremity neuromuscular performance.
  • No history of lower extremity surgery in the past 12 months.

Exclusion Criteria:

  • Individuals younger than 18 or older than 30.
  • Acute lower extremity injury in the last 12 weeks.
  • Lower extremity surgery within the last 12 months.
  • Pain in either lower extremity that would limit maximal physical exertion.
  • History of neurological disorders, including but not limited to: Neuropathy, Stoke, MS, Parkinson's Disease, etc.
  • Use of medications that significantly impact neuromuscular performance, strength or fatigue.
  • No supplementation that affects neuromuscular performance, strength, or fatigue.
  • Unable to read and understand English.
  • Not in a vulnerable population: Pregnant, mentally or physically challenged, cognitively impaired.

Study Design

Enrollment

45 participants

Anticipated

Allocation

Randomized

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Sliders

Manually applying slider technique of neurodynamics.

active comparator: Tensioners

Manually applied tensioner, neurodynamic technique

experimental: Mechanically Loaded Neurodynamics

Externally loaded neurodynamic intervention in the slider technique.

Interventions

Sciatic Slider

Mobility of a nerve, by placing tension on one end of the nerve and slacking (removing) tension off the other side of the nerve, through a full range of motion.

Sciatic Tensioner

Loading the nerve, by placing tension on both ends of the nerve, isometrically at end range of motion.

Mechanically loaded neurodynamic sciatic floss

Placing tension on one end of the nerve while taking the tension off the other end, under external load of an elastic resistance band.

Elastic Resistance Band

Elastic resistance band was used to provide submaximal resistance during the mechanically loaded neurodynamic intervention.

Primary outcome measure

  • Isometric Strength [ Time Frame: From initial strength and endurance test, to the post intervention strength and endurance test, assessed during a single study visit, assessed up to 30 minutes. ]

Central Contacts and Locations

Central contacts

Dr. Tommy Wyat, DPT

856-381-6652twyatt2@highpoint.edu

Locations

High Point University

Recruiting

High Point, North Carolina, United States, 27268

Contacts

Dr. Tommy Wyatt, DPT

856-381-6652twyatt2@highpoint.edu

Principal Investigator:

Tommy Wyatt, DPT

More Information

Sponsor

High Point University

Last update posted

Jul 22, 2026

Last verified

Jul, 2026

Keywords

  • hamstring
  • sciatic nerve
  • athlete

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by High Point University on 2026-07-22.