Recruiting

Cervical Manual Therapy

Sponsor:

Florida Gulf Coast University

Code:

NCT07725198

Conditions

Head and Neck

Headache

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Interventions

Thrust long-axis manipulation of C1-C2

Study Details

Brief summary:

This study used a prospective, randomized, repeated-measures experimental design to investigate the immediate effects of two upper cervical manual therapy interventions on craniovertebral angle (CVA), clinician-perceived atlas position, and musculoskeletal ultrasound-derived obliquus capitis inferior (OCI) muscle morphology

Conditions

Head and Neck

Headache

Study ID

NCT07725198

Start date

May 1, 2025

Status verified date

Jul, 2026

Completion date

Jan 1, 2027

Anticipated

Primary completion date

Jan 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Inclusion Criteria:

  • read and understand English
  • no previous history of cervical spine surgery or traumatic cervical injury
  • no contraindications to cervical manual therapy

Exclusion Criteria:

  • any absolute contraindications to cervical manipulation
  • any other medical condition considered unsafe for manual therapy.

Study Design

Enrollment

80 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Long axis thrust manipulation group

A single long axis thrust manipulation C1-C3

sham comparator: Long axis thrust mobilization group

3 x 5 second Long axis traction hold of C1-C3

Interventions

Thrust long-axis manipulation of C1-C2

One thrust manipulation is provided in the thrust group. a 5 second long axis hold traction of C1-C2 was repeated 3 times in the mobilization group

Primary outcome measure

  • MSK Ultrasound [ Time Frame: before intervention, immediately after, and 24 hours after intervention ]

Central Contacts and Locations

Central contacts

Rob Sillevis, PhD

239-7454312rsillevis@fgcu.edu

Locations

Florida Gulf Coast University Marieb Hall 101

Recruiting

Fort Myers, Florida, United States, 33965

Contacts

Rob Sillevis, PhD

239-7454312rsillevis@fgcu.edu

More Information

Sponsor

Florida Gulf Coast University

Last update posted

Aug 28, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Florida Gulf Coast University on 2026-08-28.