Recruiting

Digital Health Program

Sponsor:

National Bureau of Economic Research, Inc.

Code:

NCT07725250

Conditions

Hypertension

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Digital heath tool

Low-intensity recommendation

High-intensity recommendation

Study Details

Brief summary:

This study evaluates a new digital health program that uses artificial intelligence (AI) to help patients lower their blood pressure through personalized lifestyle recommendations. The program collects information about patients' daily habits and blood pressure readings, then uses AI to suggest lifestyle changes that may work best for each person. The study will measure how well this program works across different groups of patients and aims to improve the program design to make it more effective and easier to use. The program will be offered to diverse patients at UC San Diego Health, including people of different ages, genders, races/ethnicities, and economic backgrounds, as part of their regular healthcare services.

Conditions

Hypertension

Study ID

NCT07725250

Start date

Apr 10, 2026

Status verified date

Jul, 2026

Completion date

Apr 30, 2027

Anticipated

Primary completion date

Apr 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Stage I-II hypertension (average clinical readings of blood pressure over 140/90)
  • Adequate decisional capacity to make a choice about participating in this research study
  • Fully ambulatory (not requiring assistive device such as a cane, wheelchair, walker, etc.)

Exclusion Criteria:

  • Pregnancy
  • Under age 18 years
  • Institutionalized individuals who are likely to be vulnerable
  • Dependent on supplemental oxygen

Study Design

Enrollment

3000 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: RCT Arm A: Digital health tool

Participants in this arm will receive the Digital Health Tool intervention.

experimental: RCT Arm B.1: Digital health tool + low-intensity recommendations

Participants in this arm will receive the Digital Health Tool and Low-Intensity Recommendation interventions.

experimental: RCT Arm B.2: Digital health tool + high-intensity recommendations

Participants in this arm will receive the Digital Health Tool and High-Intensity Recommendation interventions.

Interventions

Digital heath tool

Digital health tool of patient-tailored lifestyle recommendations for blood pressure maintenance. Current "simplified" remote patient monitoring program referred to as "P1000." Requires daily blood pressure readings only.

Low-intensity recommendation

AI-enhanced lifestyle and health recommendations provided weekly. This requires blood pressure readings, as well as passive readings, (e.g. sleep, movement), and a daily questionnaire.

High-intensity recommendation

AI-enhanced lifestyle and health recommendations provided weekly, plus daily reminders. This requires blood pressure readings, as well as passive readings, (e.g. sleep, movement), and a daily questionnaire.

Primary outcome measure

  • Systolic blood pressure measurement [ Time Frame: 6 months ]

Central Contacts and Locations

Central contacts

Amanda Walker

617-588-1445Alw038@health.ucsd.edu

Ross Graham

rograham@health.ucsd.edu

Locations

University of California, San Diego

Recruiting

La Jolla, California, United States, 92093

Contacts

Amanda Walker

617-588-1445Alw038@health.ucsd.edu

Ross Graham

rograham@health.ucsd.edu

More Information

Sponsor

National Bureau of Economic Research, Inc.

Last update posted

Jul 24, 2026

Last verified

Jul, 2026

Keywords

  • lifestyle recommendations
  • AI/ML
  • personalized medicine

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by National Bureau of Economic Research, Inc. on 2026-07-24.