Recruiting

Ropeginterferon Alfa-2b

Sponsor:

Massachusetts General Hospital

Code:

NCT07734272

Conditions

Polycythemia Vera

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Interventions

Standardized progress note

Study Details

Brief summary:

The purpose of this quality improvement initiative is to explore whether an electronic medical records-based templated progress note for polycythemia vera (PV) in addition to a standard-of-care pharmacist-collaborative ropeginterferon alfa-2b titration service is feasible, acceptable, and appropriate for clinicians who manage PV.

Conditions

Polycythemia Vera

Study ID

NCT07734272

Start date

Sep 11, 2026

Status verified date

Nov, 2026

Completion date

Mar 31, 2028

Anticipated

Primary completion date

Dec 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Inclusion Criteria:

\- Hematologists and medical oncologists within the Mass General Brigham network sites who treat at least one patient with PV in their outpatient clinic.

Exclusion Criteria:

  • Clinicians who do not have an outpatient hematology or medical oncology clinic within Mass General Brigham.
  • Clinicians who do not utilize the EPIC electronic medical record (EMR) System as their method of patient progress note documentation.

Study Design

Enrollment

32 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Standardized note with standard-of-care pharmacist support

Standardized progress note templates with opt-in option for standard-of-care pharmacist support of ropeginterferon alfa-2b titration

Interventions

Standardized progress note

Pilot intervention will include a standardized progress note for PV patient visits in addition to a standard-of-care opt-in for pharmacist-led titration for patients on ropeginterferon alfa-2b.

Primary outcome measure

  • Feasibility of intervention [ Time Frame: 12 months ]

Central Contacts and Locations

Central contacts

Michelle Lee, MD

617-882-6060mlee37@mgb.org

Locations

Mass General Brigham Cancer Institute

Recruiting

Boston, Massachusetts, United States, 02114

Contacts

Michelle Lee, MD

617-882-6060MLee37@mgb.org

More Information

Sponsor

Massachusetts General Hospital

Last update posted

Nov 13, 2026

Last verified

Nov, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-11-14. This information was provided to ClinicalTrials.gov by Massachusetts General Hospital on 2026-11-13. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.