Recruiting

EUS Guided RFA

Sponsor:

The University of Texas Health Science Center, Houston

Code:

NCT07737171

Conditions

Pancreatic Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA)

Study Details

Brief summary:

This is a 7-year prospective single-center registry study to assess the safety and efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the treatment of pancreatic lesions.

Conditions

Pancreatic Cancer

Study ID

NCT07737171

Start date

Apr 7, 2026

Status verified date

Jul, 2026

Completion date

Apr 1, 2033

Anticipated

Primary completion date

Apr 1, 2033

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Diagnosis of any pancreatic pre-malignant lesion and/or pancreatic malignancy
  • Patients already undergoing EUS-RFA for treatment of pancreatic lesions clinically

Exclusion Criteria:

  • Patients with co-existing malignancies of other organs (or a prior history of such)
  • Patients unable to provide informed consent
  • Patients unable to complete follow-up

Study Design

Enrollment

60 participants

Anticipated

Interventions and Outcome Measures

Arms

Adult patients who undergo EUS-RFA for treatment of pancreatic lesions

Interventions

Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA)

EUS-guided Radiofrequency Ablation (RFA) consists of the application of alternating current with a frequency of 350-500 kHz (coincidentally the frequency range of radio broadcasts as well) to the target tissue via a special electrode located at the tip of the endoscope.

Primary outcome measure

  • Number of participants for whom there is technical success of tumor treatment [ Time Frame: From time of the procedure to about 3 months post procedure ]

Central Contacts and Locations

Central contacts

Amatullah Alibhai, MBA

713-500-6658Amatullah.Alibhai@uth.tmc.edu

Nicole Fatheree, BBA

713-500-5669Nicole.Fatheree@uth.tmc.edu

Locations

The University of Texas Health Science Center at Houston

Recruiting

Houston, Texas, United States, 77030

Contacts

Amatullah Alibhai, MBA

713-500-6658Amatullah.Alibhai@uth.tmc.edu

Nicole Fatheree, BBA

713-500-5669Nicole.Fatheree@uth.tmc.edu

More Information

Sponsor

The University of Texas Health Science Center, Houston

Last update posted

Jul 30, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-04. This information was provided to ClinicalTrials.gov by The University of Texas Health Science Center, Houston on 2026-07-30. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.