Sponsor:
University of Iowa
Code:
NCT07738003
Conditions
Autism Disorders and Maternal Stress
Development Delay
Prenatal Stress
Social Behavior
Eligibility Criteria
Sex: All
Age: 0 - 50
Healthy Volunteers: Accepted
Interventions
Change in child's DNA methylation
Perinatal stress
Early social experience
Polygenic risk scores for social communication and repetitive behavior
Brief summary:
Conditions
Autism Disorders and Maternal Stress
Development Delay
Prenatal Stress
Social Behavior
Study ID
NCT07738003
Start date
May 12, 2026
Status verified date
Jul, 2026
Completion date
May, 2030
Anticipated
Primary completion date
May, 2029
Anticipated
Eligibility Criteria
Sex: All
Age: 0 - 50
Healthy Volunteers: Accepted
Enrollment
7200 participants
Anticipated
Arms
Pregnant women/mothers
Children with autism spectrum disorder (ASD)
Group with developmental delay (but no ASD)
Typically developing (TD) group
Interventions
Change in child's DNA methylation
Perinatal stress
Early social experience
Polygenic risk scores for social communication and repetitive behavior
Primary outcome measure
Central contacts
Locations
Center fro Disabilities and Development
Recruiting
Iowa City, Iowa, United States, 52246
Contacts
Principal Investigator:
Lane Strathearn, MBBS FRACP PhD
Sponsor
University of Iowa
Last update posted
Aug 3, 2026
Last verified
Jul, 2026
Keywords
Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by University of Iowa on 2026-08-03.