Recruiting

Proton Therapy

Sponsor:

University of Wisconsin, Madison

Code:

NCT07759999

Conditions

Proton Therapy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Treatment Planning Software

Study Details

Brief summary:

Researchers are doing this study to better understand how certain treatment planning and clinical workflow software systems support the delivery of standard-of-care proton radiation therapy.

The main question it aims to answer is how well the software works in the workflow.

Participants will receive proton therapy.

Conditions

Proton Therapy

Study ID

NCT07759999

Start date

Jul 15, 2026

Status verified date

Aug, 2026

Completion date

Sep, 2027

Anticipated

Primary completion date

Sep, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥ 18 years at the time of consent.
  • Participant is deemed clinically appropriate for standard-of-care proton therapy by treating radiation oncologist and will not require anesthesia for therapy.
  • Ability to understand and the willingness to sign a written informed consent document.

Exclusion Criteria:

  • Participant has contraindications to proton therapy (per standard clinical guidelines).
  • Participant is unable to comply with routine treatment workflow or follow-up.
  • Participants who will be treated with a radiation plan of 5 fractions or fewer.

Study Design

Enrollment

180 participants

Anticipated

Intervention Model

Single group

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: Treatment Planning Software

Interventions

Treatment Planning Software

Uniform application of RayTracker and RayAdaptive software analyses for every verification image taken during proton therapy.

Primary outcome measure

  • Proportion of verification image assessments resulting in an adaptive replanning decision [ Time Frame: From the first verification image assessment through completion of proton therapy, up to 22 weeks ]

Central Contacts and Locations

Central contacts

Cancer Connect

800-622-8922clinicaltrials@cancer.wisc.edu

Locations

University of Wisconsin Hospital and Clinics (Carbone Cancer Center)

Recruiting

Madison, Wisconsin, United States, 53792

Contacts

UWCCC Cancer Connect

1-800-622-8922clinicaltrials@cancer.wisc.edu

More Information

Sponsor

University of Wisconsin, Madison

Last update posted

Aug 12, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Wisconsin, Madison on 2026-08-12.